Results 131 to 140 of about 366,264 (296)
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Distinct Biotypes of Visual Perception in Major Depressive Disorder
Advanced Science, EarlyView.In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai +13 more
wiley +1 more source
Neuroimaging in drug resistant epilepsy
International Journal of Research in Medical Sciences, 2018 Background: Epilepsy is a common serious neurological condition and 30 to 40 % of people with epilepsy have seizures that are not controlled by medication. Patients are considered to have drug resistant epilepsy if disabling seizures continue despite appropriate trials of two anti-epileptic drugs.
Namrita Sachdev +2 more
openaire +2 more sources
Language recovery after epilepsy surgery of the Broca's area
Epilepsy and Behavior Case Reports, 2018 Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery.
Lilit Mnatsakanyan +6 more
doaj +1 more source
The Overlap between Headache and Epilepsy in the Light of Recent Advances in Medical Genetics [PDF]
, 2014 Not ...
A. Ferretti +2 more
core +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2012 Objective To observe the expressions of heat shock 27 ⁃ associated protein 1 (HSPBAP1) and echinoderm microtubule⁃associated protein⁃like 5 (EML5) in cerebrospinal fluid of drug⁃ resistant epilepsy, and to explore the value in early diagnosis of epilepsy.
Yun CHEN +6 more
doaj
Frontiers in NeurologyEpilepsy is one of the most common nervous system diseases, which is characterized by recurrent seizures caused by abnormal neuronal discharges in the brain. Drug-resistant epilepsy (DRE) brings great challenges to clinical treatment.
Yanqiu Huang, Yangfan Zhang, Yi Liang
doaj +1 more source
Second‐hit DEPDC5 mutation is limited to dysmorphic neurons in cortical dysplasia type IIA
Annals of Clinical and Translational Neurology, 2019 Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy and is associated with pathogenic variants in mTOR pathway genes. How germline variants cause these focal lesions is unclear, however a germline + somatic “2‐hit” model is hypothesized.
Wei Shern Lee +13 more
doaj +1 more source
Efficacy and safety of eslicarbazepine acetate monotherapy in patients converting from carbamazepine. [PDF]
, 2018 OBJECTIVE: To evaluate the influence of prior use of carbamazepine (CBZ) and other antiepileptic drugs (AEDs) with a putatively similar mechanism of action (inhibition of voltage-gated sodium channels; VGSCs) on seizure outcomes and tolerability when ...
Abou-Khalil +11 more
core +2 more sources