Results 131 to 140 of about 2,749,589 (298)

Drug-resistant epilepsy treated with a vagus nerve stimulator – case report and literature review

Journal of Education, Health and Sport
The average incidence of epilepsy worldwide is estimated at 7.60 cases per 1,000 inhabitants, with an average annual incidence of 67.77 cases per 100,000 inhabitants. Epilepsy is one of the most common neurological diseases. However, it is not a disease
Michał Leśniewski, Dominika Brzuchacz, Patrycja Błaszczeć, Agata Miecznikowska, Natalia Siwak, Iwona Welian-Polus, Klaudia Szukała, Magdalena Chrościńska-Krawczyk   +7 more
doaj   +1 more source

Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences

British Journal of Clinical Pharmacology, EarlyView.
Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry, Muhammad Umair Khan, Barbara Conway, Syed Shahzad Hasan   +3 more
wiley   +1 more source

Serum α-Synuclein in Pediatric Refractory Epilepsy: Correlation with Diagnosis and Clinical Severity

Medicina
Background and Objectives: Epilepsy is a common neurological disrupt that involves recurring seizures. α-Synuclein (α-Syn), one of the most abundant proteins in the nervous system, is implicated in both neurodegenerative conditions and epilepsy.
Aida M. S. Salem, Dalia Saber Morgan, Marwa O. Elgendy, Mohamed E. A. Abdelrahim, Noura Mostafa Mohamed Mostafa, Asmaa Saleh, Manar M. Abdel-Aziz, Asmaa K. Ramadan   +7 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Siblings With Duchenne Muscular Dystrophy: Exploring Diagnosis Age and Disease Progression in a Genetic Therapy‐Naïve Cohort

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Duchenne muscular dystrophy (DMD) is the most common pediatric muscular dystrophy. Typically, there is a ~ 2‐year delay between symptom onset and diagnosis. Limited data on outcomes in early‐diagnosed individuals have limited the understanding of the clinical impact of early diagnosis.
Vaishnavi Brahmamdam, Cuixia Tian, Niki Armstrong, Valentina Pilipenko, Lisa J. Martin, Alexander Zygmunt, Irina Rybalsky, Lisa Reebals, Chinmayee B. Nagaraj   +8 more
wiley   +1 more source

Beyond the seizures: Ketogenic Diets in the battle against drug-resistant epilepsy

Journal of Education, Health and Sport
Introduction: Epilepsy is a chronic, non-infectious and one of the most common neurological disease. About 70 million people worldwide suffer from it and these are patients of all ages. Despite the existence of many anticonvulsants and multiple lines of
Natalia Domańska, Małgorzata Bojarska, Julia Bogucka, Anna Brzyska, Michalina Kosowska, Halina Piecewicz-Szczęsna   +5 more
doaj   +1 more source

Diagnosis and Treatment of Drug-Resistant Epilepsy: Present and Future Perspectives

, 2020
The introduction of the operative definition of drug-resistant epilepsy (DRE) was a turning point for clinicians and people with epilepsy (PwE) [...
Giovanni Assenza
core   +1 more source

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata, Chhitij Tiwari, Zheng Fan, Muge Gucsavas‐Calikoglu, Yael Shiloh‐Malawsky, Kimberly S. Foss, Stephanie N. Peck, Erin L. Heinzen, Chon Lee, Senyene E. Hunter   +9 more
wiley   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Measurement of Irisin, Adiponectin, and Leptin Levels in Patients with Idiopathic Epilepsy

Bezmiâlem Science
Objective: Epilepsy is a common childhood neurological disorder in which neuroinflammatory and metabolic mechanisms may contribute to epileptogenesis.
Şeyma SÖNMEZ ŞAHİN, Türkan UYGUR ŞAHİN, Tuğçe YILDIZ, Zeynep Ebru ÇAKIN, Seher DURAN, Şahabettin SELEK, Dilara Füsun İÇAĞASIOĞLU, Akın İŞCAN   +7 more
doaj   +1 more source