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Correction: Precision management of cenobamate in drug-resistant epilepsy: integrating pharmacogenetics, therapeutic drug monitoring, and real-world clinical strategies. [PDF]

open access: yesFront Pharmacol
d'Orsi G   +14 more
europepmc   +1 more source

Drug resistance in epilepsy

The Lancet Neurology, 2023
Drug resistance is estimated to affect about a third of individuals with epilepsy, but its prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other factors such as age of seizure onset and presence of associated neurological deficits.
Emilio Perucca   +3 more
openaire   +2 more sources

Drug-Resistant Epilepsy

New England Journal of Medicine, 2011
Nearly a quarter of patients with seizures have drug-resistant epilepsy. This review examines how this diagnosis should be established and how to recognize pseudoresistance. It explains possible mechanisms of drug-resistant epilepsy and presents treatment strategies.
Patrick, Kwan   +2 more
openaire   +6 more sources

Mechanisms of Apoptosis in Drug-Resistant Epilepsy

Neuroscience and Behavioral Physiology, 2022
Epilepsy is a chronic neurological disease with regular spontaneous seizures associated with neuroinflammatory, autoimmune and neurodegenerative processes. Approximately 40% of patients suffer from drug-resistant epilepsy, which leads to an increased risk of premature death, injury, irreversible brain damage, psychosocial dysfunction, and reduced ...
E.D. Bazhanova, A.A. Kozlov
openaire   +2 more sources

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