Results 171 to 180 of about 39,256 (202)

Resective Epilepsy Surgery for Drug-Resistant Focal Epilepsy

JAMA, 2015
Epilepsy surgery is indicated for patients with focal seizures who do not respond to appropriate antiepileptic drug therapy consisting of 2 or more medications.To review resective surgery outcomes for focal epilepsy, to identify which patients benefit the most, and to discuss why epilepsy surgery may not be universally accepted.Medline and Cochrane ...
Barbara C, Jobst, Gregory D, Cascino
openaire   +2 more sources

Update on Cannabidiol in Drug-Resistant Epilepsy

Indian Journal of Pediatrics
Cannabidiol (CBD) has arisen as a promising therapeutic option for children with drug-resistant epilepsy (DRE). CBD has received regulatory nod from different regulatory authorities in the United States, Europe, and India for children with DRE particularly, Dravet syndrome (DS), Lennox Gastaut syndrome (LGS), and Tuberous sclerosis complex (TSC ...
Akanksha Singh, Priyanka Madaan, Dipika Bansal   +2 more
openaire   +2 more sources

Surgical treatment of drug-resistant epilepsy

Burdenko's Journal of Neurosurgery
Background. Surgical treatment is possible for drug-resistant epilepsy. Localization of epileptogenic zone in temporal lobe or outside it influences the effectiveness of surgical treatment. Objective. To evaluate the effectiveness of surgical treatment of drug-resistant epilepsy. Material and methods.
A.A. Zuev, N.V. Pedyash, N.P. Utyashev, N.O. Ivin, A.A. Utyasheva, E.A. Gordeeva   +5 more
openaire   +2 more sources

Perampanel: A Review in Drug-Resistant Epilepsy

Drugs, 2015
Perampanel (Fycompa®), an orally-active, selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is a first-in-class antiepileptic drug (AED) offering the convenience of once-daily administration. In the EU and US, perampanel is approved in patients with epilepsy aged ≥12 years for the adjunctive ...
openaire   +2 more sources

Animal models of drug‐resistant epilepsy^*

Epileptic Disorders, 2012
ABSTRACTSeveral animal models are discussed in order to outline features of difficult‐to‐treat or drug‐resistant epilepsy. These models can be categorised as those which show a poor response to different antiepileptic drugs and those in which subgroups of drug‐resistant animals are selected, based on interindividual differences.
openaire   +2 more sources

Drug-Resistant Epilepsy

2021
Susanna O’Kula, Michael Gelfand
openaire   +1 more source

Clinical Management of Drug Resistant Epilepsy: A Review on Current Strategies

Neuropsychiatric Disease and Treatment, 2021
Deborah Guery, Sylvain Rheims
exaly  

A comparison of the gut microbiota among adult patients with drug-responsive and drug-resistant epilepsy: An exploratory study

Epilepsy Research, 2021
Hyemi Lee, Sunghee Lee, Dong-Hoon Lee
exaly  

Interneuron Transplantation for Drug-Resistant Epilepsy

Neurosurgery Clinics of North America
Current epilepsy surgical techniques, such as brain resection, laser ablation, and neurostimulation, target seizure networks macroscopically, and they may yield an unfavorable balance between seizure reduction, procedural invasiveness, and neurologic morbidity.
openaire   +2 more sources

High‐mobility group box 1 as a predictive biomarker for drug‐resistant epilepsy: A proof‐of‐concept study

Epilepsia, 2022
Lauren E Walker, Andrea Jörgensen, Jukka Peltola   +2 more
exaly