Results 171 to 180 of about 2,749,589 (298)
Seizure forecasting: The long and winding road to clinical translation
Abstract Seizure forecasting has progressed from theoretical aspiration to a rapidly advancing research domain, yet clinical translation remains limited. Over the past decades, advances in algorithm development, chronic electroencephalography (EEG), wearable sensors, and the characterization of seizure cycles have demonstrated that seizure risk is not ...
Philippa J. Karoly +7 more
wiley +1 more source
Network-based biomarkers in pediatric drug-resistant epilepsy. [PDF]
Lim J, Cho J, Kim H.
europepmc +1 more source
Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sham‐controlled crossover trial, 12 patients with DRE underwent both LIFU and
Chien‐Chen Chou +8 more
wiley +1 more source
Modern approaches to treating drug-resistant epilepsy - ketogenic diet, innovative drugs and neurosurgery [PDF]
Introduction and objective Drug-resistant epilepsy (DRE) is a type of epilepsy where seizures persist despite treatment with multiple antiepileptic drugs being implemented.
Furlepa, Natalia +9 more
core
Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku +4 more
wiley +1 more source
A comprehensive review of deep brain stimulation for drug-resistant epilepsy. [PDF]
Sasaki R +3 more
europepmc +1 more source
Abstract Objective Traumatic brain injury (TBI) induces widespread and persistent neuroinflammation, which is increasingly recognized as a key contributor to chronic sequelae including posttraumatic epilepsy (PTE), cognitive deficits, and neuropsychiatric disturbances. However, reliable biomarkers for identifying individuals at risk for these long‐term
Mohit Javalgekar +14 more
wiley +1 more source
Abstract Objective Subclinical seizures (SCSs) remain an understudied aspect of presurgical evaluation in patients with drug‐resistant epilepsy (DRE), with uncertain prevalence, distribution among epilepsy types, and predictive value for surgical outcomes.
Pilar Bosque‐Varela +6 more
wiley +1 more source
The gut microbiome and drug-resistant epilepsy: Microbiome-antiseizure medication interactions and implications for pharmacoresistance. [PDF]
Zammar K +4 more
europepmc +1 more source

