Results 271 to 280 of about 2,749,589 (298)
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Perampanel: A Review in Drug-Resistant Epilepsy
Drugs, 2015Perampanel (Fycompa®), an orally-active, selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is a first-in-class antiepileptic drug (AED) offering the convenience of once-daily administration. In the EU and US, perampanel is approved in patients with epilepsy aged ≥12 years for the adjunctive ...
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Animal models of drug‐resistant epilepsy*
Epileptic Disorders, 2012ABSTRACTSeveral animal models are discussed in order to outline features of difficult‐to‐treat or drug‐resistant epilepsy. These models can be categorised as those which show a poor response to different antiepileptic drugs and those in which subgroups of drug‐resistant animals are selected, based on interindividual differences.
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Interneuron Transplantation for Drug-Resistant Epilepsy
Neurosurgery Clinics of North AmericaCurrent epilepsy surgical techniques, such as brain resection, laser ablation, and neurostimulation, target seizure networks macroscopically, and they may yield an unfavorable balance between seizure reduction, procedural invasiveness, and neurologic morbidity.
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Surgery for Drug-Resistant Epilepsy in Children
New England Journal of Medicine, 2018Bertil, Rydenhag +2 more
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Downregulation of MicroRNA-34c-5p facilitated neuroinflammation in drug-resistant epilepsy
Brain Research, 2020Zhi-Ping Li, Yonghua Ji, Jie Tao
exaly