Results 141 to 150 of about 5,794,088 (264)

2013\u20132014 National Roadside Study of Alcohol and Drug Use by Drivers: Drug Results

open access: yes
DTNH22-11-C-00216LThis was a nationally representative study to estimate the prevalence of alcohol and other drug use among drivers. Drugs studied included 98 over-the-counter, prescription, and illegal substances.
Compton, Richard P.   +10 more
core   +1 more source

Influence of age, sex and seriousness on reporting of adverse drug reactions in Sweden

open access: yes, 2017
Purpose: To investigate how reporting of adverse drug reactions (ADRs) among adults in Sweden is associated to age and sex, in addition to seriousness of the reaction and drug utilisation.
Holm, L.,   +2 more
core   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto   +12 more
wiley   +1 more source

BALANCING FOOD SAFETY AND RISK: DO DRUG RESIDUE LIMITS AFFECT INTERNATIONAL TRADE IN BEEF? [PDF]

open access: yes
There have been a number of high profile food safety disputes in trade over the past decade. These include the widely publicized dispute at the World Trade Organization between the U.S. and EU over hormone treated beef.
Majumdar, Baishali   +2 more
core  

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

The Effects of Pharmaceutical Marketing and Promotion on Adverse Drug Events and Regulation [PDF]

open access: yes
This paper analyzes the relationship between postmarketing promotional activity and reporting of adverse drug events by modeling the interaction between a welfare maximizing regulator (the FDA) and a profit maximizing firm.
Sara Markowitz, Guy David, Seth Richards
core  

Pharmacovigilance: A Necessary Tool for Drug Safety Monitoring Globally: Pharmacovigilance

open access: yes
Pharmacovigilance, which is like a parasol to define the procedures for monitoring and analysing adverse drug reactions (ADRs), is a crucial part of efficient clinical practise, public health initiatives, and drug control systems.
Mansuri, Asra, Zaman, Tabrez Uz
core   +1 more source

Taking control: pathways to drug policies that work. [PDF]

open access: yes, 2014
In this report, we set out a broad roadmap for getting drugs under control. We recognize that past approaches premised on a punitive law enforcement paradigm have failed, emphatically so.

core  

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou   +6 more
wiley   +1 more source

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