Results 171 to 180 of about 5,794,088 (264)

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source

Present and Future Post-marketing Drug Safety Assessment in Japan: A PMDA Perspective. [PDF]

Ther Innov Regul Sci
Waki T, Watanabe S, Ando T, Kajiyama K, Fukuda K, Iwasa E, Iwasaki Y, Iwagami M, Tanaka T, Maeda D, Uyama Y.   +10 more
europepmc   +1 more source

Effect Modification of Cigarette Smoking on the Relationship Between Posttraumatic Stress Disorder, Other Mental Health Conditions, and Rheumatoid Arthritis Risk: A Large Case‐Control Study in US Veterans

Arthritis Care &Research, EarlyView.
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr, Harlan Sayles, Tate M. Johnson, Joshua F. Baker, Punyasha Roul, Grant W. Cannon, Gary A. Kunkel, Katherine D. Wysham, Gail S. Kerr, Amir A. Razmjou, Isaac Smith, Jennifer L. Barton, Maria I. Danila, Jonathan S. Richards, Bryant R. England, Ted R. Mikuls   +15 more
wiley   +1 more source

The promise of cardiomyocyte computational models for drug safety. [PDF]

Mil Med Res
Wang L, Rodriguez B.
europepmc   +1 more source

Development of Patient‐Reported Outcome Measures for Early Systemic Sclerosis Across Disease Subtypes

Arthritis Care &Research, Accepted Article.
Objective Existing patient‐reported outcome (PRO) measures for systemic sclerosis (SSc) have important limitations, including inadequate coverage of early disease and limited inclusion of diffuse cutaneous (dcSSc) and limited cutaneous (lcSSc) subtypes.
George J. Greene, Chelsea Rose Perschon, Emilie Jaeger, Alain Lescoat, David Cella, Dinesh Khanna   +5 more
wiley   +1 more source

A Methodological Review of Simulation Studies Published in Pharmacoepidemiology and Drug Safety. [PDF]

Pharmacoepidemiol Drug Saf
Muddiman R, Battan FIA, Tazare J, Schultze A, Boland F, Perez T, Wei L, Walsh ME, Moriarty F.   +8 more
europepmc   +1 more source

Generative Artificial Intelligence in Clinical Practice: How Should Rheumatologists Evaluate and Monitor Emerging Tools?

Arthritis Care &Research, EarlyView.
Generative artificial intelligence (AI) is increasingly being used in rheumatology practice, to assist with tasks such as documentation, record summarization, and clinical decision support. Rheumatologists need a practical approach to determining what evidence and oversight each application requires.
Koushan Kouranloo, Mrinalini Dey, Jinoos Yazdany   +2 more
wiley   +1 more source

How Machine Learning Can Help Close Evidence Gaps for Drug Safety in Pregnant Women. [PDF]

J Med Internet Res
Falci M.
europepmc   +1 more source

Oral glucocorticoids added to ILD‐modifying therapy in systemic sclerosis‐associated interstitial lung disease: a target trial emulation study from the EUSTAR database.

Arthritis Care &Research, Accepted Article.
Objectives We aimed to estimate whether adding oral glucocorticoids to ILD‐modifying therapy improves 12‐month lung outcomes in systemic sclerosis‐associated interstitial lung disease (SSc‐ILD). Methods We emulated a target trial using the EUSTAR database.
Zubeyir Salis, Simona Truglia, Oliver Distler, Gábor Kumánovics, Gianluca Moroncini, David Launay, Silvia Bellando‐Randone, Gonçalo Boleto, Nicoletta Del Papa, Ana Maria Gheorghiu, Duygu Temiz Karadag, Zguro Batalov, Gabriella Szucs, Michele Iudici, The EUSTAR collaborators   +14 more
wiley   +1 more source

Density Measurement of Irradiated and Nonirradiated Zirconium Oxide by Ptychographic X‐Ray Computed Tomography (PXCT)

Advanced Engineering Materials, EarlyView.
Mass density governs the protective behavior of oxide layers on nuclear fuel cladding. Ptychographic X‐ray computed tomography measures zirconium oxide grown on Zircaloy‐4 under reactor and autoclave conditions, revealing nearly identical bulk densities of 5.1 ± 0.80 g cm−3.
Okan Yetik, Liliana I. Duarte, Malgorzata G. Makowska, Roland Brütsch, Andrej Bullemer, Ana Diaz, Mirko Holler, Andreas Menzel, Johannes Bertsch, Pavel Trtik   +9 more
wiley   +1 more source