Results 11 to 20 of about 634,895 (315)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Letrozole is one of the most prescribed drugs for the treatment of breast cancer in post-menopausal women, and it is endowed with selective peripheral aromatase inhibitory activity.
Michele De Luca +6 more
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Pharmaceuticals, 2023 Analyzing urine is common in drug-facilitated sexual assault cases if the analysis of blood is not optimal. The efficient enzymatic pretreatment of urine is important for cleaving glucuronides and improving the detection of the parent drug.
Kathrine Skov +4 more
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Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
eLife, 2021 BLM (Bloom syndrome protein) is a RECQ-family helicase involved in the dissolution of complex DNA structures and repair intermediates. Synthetic lethality analysis implicates BLM as a promising target in a range of cancers with defects in the DNA damage ...
Xiangrong Chen +13 more
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Influence of manufacturing procedure on stability of Unguentum contra perniones preparations [PDF]
Vojnosanitetski Pregled, 2005 Background. Application of various technological procedures for the manufacture of officinal preparation ointment against chilblains (Unguentum contra perniones) produce essential variations in the quality and stability of the final product. Changing the
Bošković Mirjana +1 more
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Review of binary, ternary and quaternary mixtures for induction and maintenance of opioid free anesthesia [PDF]
Farmacia Hospitalaria, 2021 Objective: To describe and organize the current information available on binary, ternary and/or quaternary mixtures used in opioid-free anesthesia (OFA), as well as their physicochemical stability, in order to facilitate its correct administration ...
Beatriz Tauste-Hernández +3 more
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Challenges of Dissolution Methods Development for Soft Gelatin Capsules
Pharmaceutics, 2021 Recently, the development of soft gelatin capsules (SGCs) dosage forms has attracted a great deal of interest in the oral delivery of poorly water-soluble drugs.
Festo Damian +4 more
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Molecules, 2021 The evolution of different antimicrobial drugs in terrestrial, microgravity and hypergravity conditions is presented within this review, in connection with their implementation during human space exploration.
Ágota Simon +3 more
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Pharmaceutics, 2023 Background: Stability study of a 10 mg/mL injectable cisatracurium solution stored refrigerated in amber glass ampoules for 18 months (M18). Methods: 4000 ampoules were aseptically compounded using European Pharmacopoeia (EP)-grade cisatracurium besylate,
Marine Roche +7 more
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Prevalence of tablet splitting in a Brazilian tertiary care hospital
Pharmacy Practice, 2020 Background: Although a highly common practice in hospital care, tablet splitting can cause dose variation and reduce drug stability, both of which impair drug therapy. Objective: To determine the overall prevalence of tablet splitting in hospital care
Vivianne V. Melo +6 more
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Jornal de Pediatria, 2009 OBJETIVO: Verificar o potencial hidrogeniônico (pH) de soluções de cloridrato de dobutamina sob condições ambientais que mimetizam unidades de cuidados intensivos neonatais.
Lidiane L. Reis +2 more
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