Results 11 to 20 of about 7,797,679 (378)

Glycopeptide antibiotic drug stability in aqueous solution [PDF]

open access: yesAAPS Open, 2022
Glycopeptide antimicrobials are a class of naturally occurring or semi-synthetic glycosylated products that have shown antibacterial activity against gram-positive organisms by inhibiting cell-wall synthesis.
Sardar M. Jakaria   +2 more
semanticscholar   +2 more sources

Solid-in-Oil-in-Water Emulsion: An Innovative Paradigm to Improve Drug Stability and Biological Activity [PDF]

open access: yesAAPS PharmSciTech, 2021
An emulsion is a biphasic dosage form comprising of dispersed phase containing droplets that are uniformly distributed into a surrounding liquid which forms the continuous phase.
Anali Sawant   +3 more
semanticscholar   +2 more sources

Reverse Transcriptase Inhibitors Nanosystems Designed for Drug Stability and Controlled Delivery [PDF]

open access: yesPharmaceutics, 2019
An in-depth analysis of nanotechnology applications for the improvement of solubility, distribution, bioavailability and stability of reverse transcriptase inhibitors is reported.
F. Grande   +7 more
semanticscholar   +2 more sources

A Robust Liquid Chromatographic Method for Confirmation of Drug Stability of Azithromycin in Bulk Samples, Tablets and Suspensions [PDF]

open access: yesPharmaceutics, 2017
A simple, isocratic and robust RP-HPLC method for the analysis of azithromycin was developed, validated and applied for the analysis of bulk samples, tablets and suspensions.
Alex O. Okaru   +4 more
doaj   +2 more sources

Biopolymeric Nanogel as a Drug Delivery System for Doxorubicin—Improved Drug Stability and Enhanced Antineoplastic Activity in Skin Cancer Cells [PDF]

open access: yesPharmaceuticals
In this study, doxorubicin was loaded in a chitosan–albumin nanogel with the aim of improving its stability and exploring the potential of the system in the treatment of skin cancer. Infrared spectroscopy and X-ray diffraction confirmed the encapsulation
Lyubomira Radeva   +6 more
doaj   +2 more sources

Exploring Enzymatic Hydrolysis of Urine Samples for Investigation of Drugs Associated with Drug-Facilitated Sexual Assault

open access: yesPharmaceuticals, 2023
Analyzing urine is common in drug-facilitated sexual assault cases if the analysis of blood is not optimal. The efficient enzymatic pretreatment of urine is important for cleaving glucuronides and improving the detection of the parent drug.
Kathrine Skov   +4 more
doaj   +1 more source

A review on drug stability

open access: yesInternational Journal of Science and Research Archive, 2023
Stability is crucial to the process of developing new drugs. Stability studies are regarded as a must for the acceptance and approval of any pharmaceutical product since they guarantee the stability of product quality, safety, and efficacy during the ...
Ashutosh Kumar   +6 more
semanticscholar   +1 more source

Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2022
Letrozole is one of the most prescribed drugs for the treatment of breast cancer in post-menopausal women, and it is endowed with selective peripheral aromatase inhibitory activity.
Michele De Luca   +6 more
doaj   +1 more source

Review of binary, ternary and quaternary mixtures for induction and maintenance of opioid free anesthesia [PDF]

open access: yesFarmacia Hospitalaria, 2021
Objective: To describe and organize the current information available on binary, ternary and/or quaternary mixtures used in opioid-free anesthesia (OFA), as well as their physicochemical stability, in order to facilitate its correct administration ...
Beatriz Tauste-Hernández   +3 more
doaj   +1 more source

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