Drug Stability Analysis by Raman Spectroscopy [PDF]
Pharmaceutics, 2014 Pharmaceutical drugs are available to astronauts to help them overcome the deleterious effects of weightlessness, sickness and injuries. Unfortunately, recent studies have shown that some of the drugs currently used may degrade more rapidly in space ...
Chetan Shende +3 more
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Cyclodextrins and Their Derivatives as Drug Stability Modifiers. [PDF]
Pharmaceuticals (Basel), 2023 Cyclodextrins (CDs) are cyclic oligosaccharides that contain a relatively hydrophobic central cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion complexes with many substances.
Aiassa V, Garnero C, Zoppi A, Longhi MR.
europepmc +6 more sources
Drug Stability: ICH versus Accelerated Predictive Stability Studies [PDF]
Pharmaceutics, 2022 The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), along with the World Health Organization (WHO), has provided a set of guidelines (ICH Q1A-E, Q3A-B, Q5C, Q6A-B) intended to unify the standards
Olga González-González +6 more
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Glycopeptide antibiotic drug stability in aqueous solution. [PDF]
AAPS Open, 2022 Glycopeptide antimicrobials are a class of naturally occurring or semi-synthetic glycosylated products that have shown antibacterial activity against gram-positive organisms by inhibiting cell-wall synthesis.
Jakaria SM, Budil DE, Murtagh J.
europepmc +2 more sources
Solid-in-Oil-in-Water Emulsion: An Innovative Paradigm to Improve Drug Stability and Biological Activity. [PDF]
AAPS PharmSciTech, 2021 An emulsion is a biphasic dosage form comprising of dispersed phase containing droplets that are uniformly distributed into a surrounding liquid which forms the continuous phase.
Sawant A, Kamath S, Kg H, Kulyadi GP.
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Reverse Transcriptase Inhibitors Nanosystems Designed for Drug Stability and Controlled Delivery. [PDF]
Pharmaceutics, 2019 An in-depth analysis of nanotechnology applications for the improvement of solubility, distribution, bioavailability and stability of reverse transcriptase inhibitors is reported.
Grande F +7 more
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Nanocrystals of Poorly Soluble Drugs: Drug Bioavailability and Physicochemical Stability [PDF]
Pharmaceutics, 2018 Many approaches have been developed over time to overcome the bioavailability limitations of poorly soluble drugs. With the advances in nanotechnology in recent decades, science and industry have been approaching this issue through the formulation of ...
M. Gigliobianco +3 more
semanticscholar +8 more sources
A Robust Liquid Chromatographic Method for Confirmation of Drug Stability of Azithromycin in Bulk Samples, Tablets and Suspensions [PDF]
Pharmaceutics, 2017 A simple, isocratic and robust RP-HPLC method for the analysis of azithromycin was developed, validated and applied for the analysis of bulk samples, tablets and suspensions.
Alex O. Okaru +4 more
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Long-Term Amorphous Drug Stability Predictions Using Easily Calculated, Predicted, and Measured Parameters [PDF]
Molecular Pharmaceutics, 2015 The purpose of this study was to develop a predictive model of the amorphous stability of drugs with particular relevance for poorly water-soluble compounds.
Katarzyna Nurzyńska +5 more
openalex +2 more sources
Biopolymeric Nanogel as a Drug Delivery System for Doxorubicin—Improved Drug Stability and Enhanced Antineoplastic Activity in Skin Cancer Cells [PDF]
PharmaceuticalsIn this study, doxorubicin was loaded in a chitosan–albumin nanogel with the aim of improving its stability and exploring the potential of the system in the treatment of skin cancer. Infrared spectroscopy and X-ray diffraction confirmed the encapsulation
Lyubomira Radeva +6 more
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