Results 11 to 20 of about 8,056,631 (393)

The Value of Drug Stability Studies and Their Publication. [PDF]

Can J Hosp Pharm, 2018
Brown G.
europepmc   +3 more sources

Stability of furosemide and torasemide in parenteral nutrition admixture [PDF]

Acta Poloniae Pharmaceutica, 2023
Furosemide and torasemide (loop diuretics) are used to treat hypertension or pulmonary edema. They are often administered in the parenteral route. In critically ill patients, there is a problem of a limited number of venous accesses, which complicates ...
Szymon Tomczak, Anna Jelińska, Jan Kościński   +2 more
doaj   +1 more source

Stability Tests and Analytical Methods of Tacrolimus: A Review [PDF]

ImmunoAnalysis, 2022
Tacrolimus is an immunosuppressive drug widely used in organ or tissue transplantation. Furthermore, its anti-inflammatory effects are employed in treatments for psoriasis, uveitis, and vernal keratoconjunctivitis.
Sara Sajjadi, Mohammadreza Siahi-Shadbad, Mohammad Reza Afshar Mogaddam   +2 more
doaj   +1 more source

Pharmaceutical co-crystals: A green way to enhance drug stability and solubility for improved therapeutic efficacy.

The Journal of pharmacy and pharmacology, 2023
Pharmaceutical co-crystals have gained significant attention in recent years as a promising green and sustainable method for poorly soluble drugs to improve their solubility, stability, and bioavailability.
Anisha Chettri, Ankita Subba, G. P. Singh, P. Bag   +3 more
semanticscholar   +1 more source

Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Letrozole is one of the most prescribed drugs for the treatment of breast cancer in post-menopausal women, and it is endowed with selective peripheral aromatase inhibitory activity.
Michele De Luca, Maria Antonietta Occhiuzzi, Bruno Rizzuti, Giuseppina Ioele, Gaetano Ragno, Antonio Garofalo, Fedora Grande   +6 more
doaj   +1 more source

Exploring Enzymatic Hydrolysis of Urine Samples for Investigation of Drugs Associated with Drug-Facilitated Sexual Assault

Pharmaceuticals, 2023
Analyzing urine is common in drug-facilitated sexual assault cases if the analysis of blood is not optimal. The efficient enzymatic pretreatment of urine is important for cleaving glucuronides and improving the detection of the parent drug.
Kathrine Skov, Sys Stybe Johansen, Kristian Linnet, Brian Schou Rasmussen, Marie Katrine Klose Nielsen   +4 more
doaj   +1 more source

A review on drug stability

International Journal of Science and Research Archive, 2023
Stability is crucial to the process of developing new drugs. Stability studies are regarded as a must for the acceptance and approval of any pharmaceutical product since they guarantee the stability of product quality, safety, and efficacy during the ...
Ashutosh Kumar, A. Yadav, Abhishek Yadav, Manish Yadav, Md Akhlak, Shweta Mishra, J. Kumar   +6 more
semanticscholar   +1 more source

Influence of manufacturing procedure on stability of Unguentum contra perniones preparations [PDF]

Vojnosanitetski Pregled, 2005
Background. Application of various technological procedures for the manufacture of officinal preparation ointment against chilblains (Unguentum contra perniones) produce essential variations in the quality and stability of the final product. Changing the
Bošković Mirjana, Toskić-Radojičić Marija   +1 more
doaj   +1 more source

Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein

eLife, 2021
BLM (Bloom syndrome protein) is a RECQ-family helicase involved in the dissolution of complex DNA structures and repair intermediates. Synthetic lethality analysis implicates BLM as a promising target in a range of cancers with defects in the DNA damage ...
Xiangrong Chen, Yusuf I Ali, Charlotte EL Fisher, Raquel Arribas-Bosacoma, Mohan B Rajasekaran, Gareth Williams, Sarah Walker, Jessica R Booth, Jessica JR Hudson, S Mark Roe, Laurence H Pearl, Simon E Ward, Frances MG Pearl, Antony W Oliver   +13 more
doaj   +1 more source

Stability of Antimicrobial Drug Molecules in Different Gravitational and Radiation Conditions in View of Applications during Outer Space Missions

Molecules, 2021
The evolution of different antimicrobial drugs in terrestrial, microgravity and hypergravity conditions is presented within this review, in connection with their implementation during human space exploration.
Ágota Simon, Adriana Smarandache, Vicentiu Iancu, Mihail Lucian Pascu   +3 more
doaj   +1 more source