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Teratogenic Risks of Drug Synergism
Nature, 1964IT is well known that the effectiveness of teratogens, measured either in incidence or in severity of resulting malformations, is frequently modified, in a plus or minus direction, by unrelated external conditions. The mechanisms by which these modifying agencies operate are largely unknown.
W, LANDAUER, E M, CLARK
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The interaction index: a measure of drug synergism
Pain, 2002Two drugs used in combination may produce enhanced or reduced effects. The degree of enhancement or reduction is measured from the interaction index (gamma), a quantity that indicates the changed potency of the combination. The index is therefore a quantitative marker for the drug combination and effect metric used.
R. Tallarida
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Informatics of Drug Synergism in Naturally Occurring Anticancer Agents
Recent Patents on Anti-Cancer Drug Discovery, 2011Cancer is a multi-factorial disease resulting in uncontrolled division of body cells, with difficult and complex suppression. The main treatment strategy for this disease depends on killing of tumor cells that usually exist in the proximity of normal body cells. During the course of treatment, the healthy cells should not be affected by the toxic doses
Ghazaleh, Ghavami +2 more
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ANTIBODY-DRUG SYNERGISM: AN ASSESSMENT OF SPECIFIC PASSIVE IMMUNOTHERAPY IN BRONCHIAL CARCINOMA
Lancet, The, 1977C E Newman, C E Newman, C H Ford
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Drug Synergism in Antineoplastic Chemotherapy
Advances in chemotherapy, 1964J M, VENDITTI, A, GOLDIN
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