Results 231 to 240 of about 4,420,912 (284)

Predicting Drug Synergism by Means of Non-Negative Matrix Tri-Factorization

IEEE/ACM Transactions on Computational Biology & Bioinformatics, 2021
Traditional drug experiments to find synergistic drug pairs are time-consuming and expensive due to the numerous possible combinations of drugs that have to be examined.
Pietro Pinoli, G. Ceddia, S. Ceri, M. Masseroli   +3 more
semanticscholar   +1 more source

Synergism of rotenone by piperonyl butoxide in Haemonchus contortus and Trichostrongylus colubriformis in vitro: Potential for drug-synergism through inhibition of nematode oxidative detoxification pathways

Veterinary Parasitology, 2006
R J Dobson, R J Dobson, A C Kotze
exaly   +2 more sources

Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics.

Seminars in Cancer Biology, 2020
The frequent inefficiency of conventional cancer therapies due to drug resistance, non-targeted drug delivery, chemotherapy-associated toxic side effects turned the focus to bioactive phytochemicals.
S. Patra, Biswajita Pradhan, Rabindra Nayak, C. Behera, L. Rout, M. Jena, T. Efferth, S. Bhutia   +7 more
semanticscholar   +1 more source

TREATMENT OF MELANOMA BY PASSIVE HUMORAL IMMUNOTHERAPY USING ANTIBODY DRUG SYNERGISM

Lancet, The, 1977
G F Rowland, D A Davies
exaly   +2 more sources

Sequential Blockage as a Theoretical Basis for Drug Synergism

Journal of Medicinal Chemistry, 1963
M. L. Black
openaire   +3 more sources

Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19

Journal of Biomolecular Structure and Dynamics, 2020
A novel coronavirus (SARS-CoV-2) has caused a major outbreak in humans all over the world, and it is the latest pandemic in the series of other infectious diseases.
Nisha Muralidharan, R. Sakthivel, D. Velmurugan, M. Gromiha   +3 more
semanticscholar   +1 more source

A further comment on testing for drug synergism

Pain, 1992
R. Tallarida
openaire   +2 more sources

Bienzymatic synergism of vanadium oxide nanodots to efficiently eradicate drug-resistant bacteria during wound healing in vivo.

Journal of Colloid and Interface Science, 2020
Antibiotic resistance is a common phenomenon observed during treatment with antibacterials. Use of nanozymes, especially those with synergistic enzyme-like activities, as antibacterials could overcome this problem, but their synthesis is limited by their
Weishuai Ma, Tingting Zhang, Ronggui Li, Yusheng Niu, Xuecheng Yang, Jing Liu, Yuanhong Xu, C. Li   +7 more
semanticscholar   +1 more source

Communicating Synergism in Drug Combination Studies

Arzneimittelforschung, 2011
Isobolograms are used to identify synergistic effects of drugs given in combination. However, the traditional isobologram provides only a qualitative determination of synergism. The present report describes two procedures for quantifying the synergistic actions of drugs based on isobolographic plots.
J, Brodkin, H E, Shannon
openaire   +2 more sources

Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane.

Molecular and Cellular Endocrinology, 2019
90 kDa heat shock proteins (Hsp90) act as protein chaperones and play a role in modulating endoplasmic reticulum (ER) stress. Hsp90 inhibitors are under clinical investigation as cancer treatment.
S. Sbiera, Sabine Kendl, I. Weigand, Iuliu Sbiera, M. Fassnacht, M. Kroiss   +5 more
semanticscholar   +1 more source