Results 51 to 60 of about 3,800,890 (227)

Effect of 5-Fluorouracil Administered at Low Doses on Cytotoxic Properties of Methotrexate in the in vivo Model of Mice L1210 Leukemia; According to the Schedule of Treatment

open access: yesPteridines, 1994
The study compared antineoplastic effects of combined methotrexate and 5-fluorouracil therapy on LI210 lymphoid leukemia in mice according to the schedule of treatment. Methotrexate was administered at doses of: LOw.. 0.5 LOw.
Graczyk Julita
doaj   +1 more source

Synergism of cationic antimicrobial peptide WLBU2 with antibacterial agents against biofilms of multi-drug resistant Acinetobacter baumannii and Klebsiella pneumoniae

open access: yesInfection and Drug Resistance, 2019
Purpose The activity of the cationic antimicrobial peptide WLBU2 was evaluated against planktonic cells and biofilms of multi-drug resistant (MDR) Acinetobacter baumannii and Klebsiella pneumoniae, alone and in combination with classical antimicrobial ...
S. Swedan, Zaina Shubair, A. Almaaytah
semanticscholar   +1 more source

Non-Steroidal Anti-Inflammatory Drugs Increase Cisplatin, Paclitaxel, and Doxorubicin Efficacy against Human Cervix Cancer Cells

open access: yesPharmaceuticals, 2020
This study shows that the non-steroidal anti-inflammatory drug (NSAID) celecoxib and its non-cyclooxygenase-2 (COX2) analogue dimethylcelecoxib (DMC) exert a potent inhibitory effect on the growth of human cervix HeLa multi-cellular tumor spheroids (MCTS)
Diana Xochiquetzal Robledo-Cadena   +8 more
doaj   +1 more source

The cardiovascular effects of midazolam co-induction to propofol for induction in aged patients [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundThe aim of this study was to investigate whether a small dose of midazolam and lessening the propofol dosage could prevent cardiovascular change at tracheal intubation for induction in aged patients.MethodsEighty patients over 65 years (ASA ...
Young Soo Lim   +7 more
doaj   +1 more source

New Trends for Antimalarial Drugs: Synergism between Antineoplastics and Antimalarials on Breast Cancer Cells

open access: yesBiomolecules, 2020
Chemotherapy plays a key role in breast cancer therapy, but drug resistance and unwanted side effects make the treatment less effective. We propose a new combination model that combines antineoplastic drugs and antimalarials for breast cancer therapy ...
Diana Duarte, Nuno Vale
doaj   +1 more source

C-1 Substituted isoquinolines potentiate the antimycobacterial activity of rifampicin and ethambutol

open access: yesFrontiers in Antibiotics, 2023
IntroductionThe emergence of extensively drug-resistant strains of Mycobacterium tuberculosis threatens decades of progress in the treatment of a disease which remains one of the leading infectious causes of death worldwide.
Liam T. Martin   +9 more
doaj   +1 more source

Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia

open access: yesScientific Reports, 2023
Despite recent relevant therapeutic progresses, chronic lymphocytic leukemia (CLL) remains an incurable disease. Selinexor, an oral inhibitor of the nuclear export protein XPO1, is active as single agent in different hematologic malignancies, including ...
Candida Vitale   +13 more
doaj   +1 more source

Synergism of interferon-beta with antiviral drugs against SARS-CoV-2 variants [PDF]

open access: green, 2022
Denisa Bojková   +7 more
openalex   +3 more sources

Computational analyses of synergism in small molecular network motifs. [PDF]

open access: yesPLoS Computational Biology, 2014
Cellular functions and responses to stimuli are controlled by complex regulatory networks that comprise a large diversity of molecular components and their interactions.
Yili Zhang   +3 more
doaj   +1 more source

Anti-cryptococcal activity of ethanol crude extract and hexane fraction from Ocimum basilicum var. Maria bonita: mechanisms of action and synergism with amphotericin B and Ocimum basilicum essential oil

open access: yesPharmaceutical Biology, 2017
Context: Ocimum basilicum L. (Lamiaceae) has been used in folk medicine to treat headaches, kidney disorders, and intestinal worms. Objective: This study evaluates the anti-cryptococcal activity of ethanol crude extract and hexane fraction obtained from ...
Nathalia N. R. Cardoso   +7 more
doaj   +1 more source

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