Results 31 to 40 of about 4,420,912 (284)

Non-active antibiotic and bacteriophage synergism to successfully treat recurrent urinary tract infection caused by extensively drug-resistant Klebsiella pneumoniae

Emerging Microbes and Infections, 2020
We report a case of a 63-year-old female patient who developed a recurrent urinary tract infection (UTI) with extensively drug-resistant Klebsiella pneumoniae (ERKp).
Juan Bao, Nannan Wu, Yigang Zeng, Liguang Chen, Linlin Li, Lan Yang, Yiyuan Zhang, Mingquan Guo, Lisha Li, Jie Li, Demeng Tan, Meng-jun Cheng, J. Gu, J. Qin, Jiazhen Liu, Shiru Li, Guang-qiang Pan, Xin Jin, Bangxin Yao, Xiaokui Guo, T. Zhu, Shuai Le   +21 more
semanticscholar   +1 more source

Allosteric cross-talk in chromatin can mediate drug-drug synergy

Nature Communications, 2017
Allostery and drug-drug synergism can yield potential novel therapies with existing molecules. Here, the authors provide evidence that two unrelated drugs have increased cytotoxicity in cancer cells, which coincides with increased formation of chromatin ...
Zenita Adhireksan, Giulia Palermo, Tina Riedel, Zhujun Ma, Reyhan Muhammad, Ursula Rothlisberger, Paul J. Dyson, Curt A. Davey   +7 more
doaj   +1 more source

Effect of 5-Fluorouracil Administered at Low Doses on Cytotoxic Properties of Methotrexate in the in vivo Model of Mice L1210 Leukemia; According to the Schedule of Treatment

Pteridines, 1994
The study compared antineoplastic effects of combined methotrexate and 5-fluorouracil therapy on LI210 lymphoid leukemia in mice according to the schedule of treatment. Methotrexate was administered at doses of: LOw.. 0.5 LOw.
Graczyk Julita
doaj   +1 more source

Increasing the Efficacy of Treatment of Staphylococcus aureus–Candida albicans Mixed Infections with Myrtenol

Antibiotics, 2022
Infectious diseases caused by various nosocomial microorganisms affect worldwide both immunocompromised and relatively healthy persons. Bacteria and fungi have different tools to evade antimicrobials, such as hydrolysis damaging the drug, efflux systems,
Ruba Y. Mahmoud, Elena Y. Trizna, Rand K. Sulaiman, Roman S. Pavelyev, Ilmir R. Gilfanov, Svetlana A. Lisovskaya, Olga V. Ostolopovskaya, Larisa L. Frolova, Alexander V. Kutchin, Galina B. Guseva, Elena V. Antina, Mikhail B. Berezin, Liliya E. Nikitina, Airat R. Kayumov   +13 more
doaj   +1 more source

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Associated with Mycoplasma pneumoniae Infection

Case Reports in Dermatology, 2020
Mycoplasma infection may lower the threshold for drug allergy in particular patients. We present a case of drug reaction with eosinophilia and systemic symptoms (DRESS), with drug etiology and non-drug etiology (Mycoplasma infection).
Guy Shalom, Raed Khoury, Amir Horev
doaj   +1 more source

The effect of crocin on the proliferation, inflammation, drug synergism, and angiogenesis in breast cancer

PHYTONutrients
Radiation, chemotherapy, and surgery are common treatments for breast cancer. These approaches, however, could only improve the odds of surviving. Using herbal medicines like crocin is now necessary to improve cancer treatment, particularly for breast ...
Seyed Hossein, Haseeba Sardar, Marzieh Lotfi   +2 more
semanticscholar   +1 more source

Development of gradient diffusion strips to identify the potentiating effect of antimicrobial compounds against multidrug-resistant Klebsiella pneumoniae strains [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. The aim of the study was to develop gradient diffusion strips with substances capable of potentiating the action of antibiotics for the treatment of infections caused by multidrug-resistant strains of K. pneumoniae.
Likhachev I.V., Kaftyreva L.A., Samoilova A.A., Kraeva L.A., Mikhailov N.V.   +4 more
doaj   +1 more source

Synergism of cationic antimicrobial peptide WLBU2 with antibacterial agents against biofilms of multi-drug resistant Acinetobacter baumannii and Klebsiella pneumoniae

Infection and Drug Resistance, 2019
Purpose The activity of the cationic antimicrobial peptide WLBU2 was evaluated against planktonic cells and biofilms of multi-drug resistant (MDR) Acinetobacter baumannii and Klebsiella pneumoniae, alone and in combination with classical antimicrobial ...
S. Swedan, Zaina Shubair, A. Almaaytah
semanticscholar   +1 more source

A Molecular and Computational Study on the Effects of 5-Fluorouracil, and Dicyclomine on AGS Cells: Regulation of P53 and SNAIL2 Pathways [PDF]

Pharmaceutical Sciences
Background: 5-Fluorouracil (5-FU) is commonly used to inhibit gastric cancer (GC) cell growth, but its clinical effectiveness is frequently limited by chemoresistance.
Fariba Ghodrati, Mahdi Bagheri, Seyedeh Yasaman Kolki, Parham Motamedi, Elham Sadeghi, Hossein Ebrahimi, Dhifaf Saleem Kareem Maliki, Hadis Musavi   +7 more
doaj   +1 more source

The cardiovascular effects of midazolam co-induction to propofol for induction in aged patients [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundThe aim of this study was to investigate whether a small dose of midazolam and lessening the propofol dosage could prevent cardiovascular change at tracheal intubation for induction in aged patients.MethodsEighty patients over 65 years (ASA ...
Young Soo Lim, Dong Hee Kang, Se Hwan Kim, Tae Ho Jang, Kyung Han Kim, Sie Jeong Ryu, Soo Bong Yu, Doo Sik Kim   +7 more
doaj   +1 more source