Results 11 to 20 of about 1,947,705 (257)
Gels, 2022 Surfactants are ubiquitous materials that are used in diverse formulations of various products. For instance, they improve the formulation of gel by improving its wetting and rheological properties. Here, we describe the effects of anionic surfactants on
Naved Azum +4 more
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Current Research in Pharmacology and Drug Discovery, 2022 Current cancer therapy includes a variety of strategies that can comprise only one type of treatment or a combination of multiple treatments. Chemotherapy is still the gold standard for cancer therapy, though sometimes associated with undesired side ...
Diana Duarte, Nuno Vale
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Computational analyses of synergism in small molecular network motifs. [PDF]
PLoS Computational Biology, 2014 Cellular functions and responses to stimuli are controlled by complex regulatory networks that comprise a large diversity of molecular components and their interactions.
Yili Zhang +3 more
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Plants, 2021 Malaria is the most lethal parasitic disease in the world. The frequent emergence of resistance by malaria parasites to any drug is the hallmark of sustained malaria burden.
Douglas O. Ochora +14 more
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Biomolecules, 2020 Chemotherapy plays a key role in breast cancer therapy, but drug resistance and unwanted side effects make the treatment less effective. We propose a new combination model that combines antineoplastic drugs and antimalarials for breast cancer therapy ...
Diana Duarte, Nuno Vale
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Allosteric cross-talk in chromatin can mediate drug-drug synergy [PDF]
Nature Communications, 2017 Allostery and drug-drug synergism can yield potential novel therapies with existing molecules. Here, the authors provide evidence that two unrelated drugs have increased cytotoxicity in cancer cells, which coincides with increased formation of chromatin ...
Zenita Adhireksan +7 more
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Quantitative methods for assessing drug synergism. [PDF]
Genes Cancer, 2011 Tallarida RJ.
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CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts. [PDF]
Sci Rep, 2022 Anticancer combination therapy has been developed to increase efficacy by enhancing synergy. Patient-derived xenografts (PDXs) have emerged as reliable preclinical models to develop effective treatments in translational cancer research. However, most PDX
Huang L +5 more
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Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Recently, there is a significant focus on combination chemotherapy for cancer using a cytotoxic drug and a phytochemical compound. We investigated the effect of silibinin on etoposide-induced apoptosis in MCF-7 and MDA-MB-231 breast ...
Mahdie Koushki +4 more
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In vitro and in vivo antimicrobial activity of an active plant-based quadrocomplex for skin hygiene [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2022 Context: The current epidemiological situation causes a new surge of interest to perspective antimicrobial formulations for proper skin hygiene. Aims: To evaluate in vitro and in vivo the antimicrobial activity of a novel active quadrocomplex (QC) for
Viktor A. Filatov +2 more
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