Multidrug resistant Enterobacterales have become a serious global health problem, with extended hospital stay and increased mortality. Antibiotic monotherapy has been reported ineffective against most drug resistant bacteria including Klebsiella ...
Julalak C Ontong +3 more
doaj +1 more source
A chemical–genetic interaction map of small molecules using high‐throughput imaging in cancer cells
Small molecules often affect multiple targets, elicit off‐target effects, and induce genotype‐specific responses. Chemical genetics, the mapping of the genotype dependence of a small molecule's effects across a broad spectrum of phenotypes can identify ...
Marco Breinig +3 more
doaj +1 more source
Editorial: Gastrointestinal and Liver Effects of Fruits and Their Synergism With Drug Therapy: Exploring Possible Mechanisms of Action [PDF]
Almir Gonçalves Wanderley +4 more
openalex +1 more source
Drug Synergism of Anticancer Action in Combination with Favipiravir and Paclitaxel on Neuroblastoma Cells. [PDF]
Turkez H +5 more
europepmc +1 more source
Complex Interactions of Lovastatin with 10 Chemotherapeutic Drugs: A Rigorous Evaluation of Synergism and Antagonism [PDF]
Kaitlyn K. Gilman +3 more
openalex +1 more source
Prediction of Drug Synergism between Peptides and Antineoplastic Drugs Paclitaxel, 5-Fluorouracil, and Doxorubicin Using In Silico Approaches. [PDF]
Vale N +5 more
europepmc +1 more source
Dose Dependent Synergism from Combination of Platinum Drugs with Curcumin Sgainst Colorectal Cancer Cell Lines [PDF]
Hana Bali +3 more
openalex +1 more source
Background and Aims Emergence of multidrug resistance in non‐fermenting Gram‐negative bacilli is a threat to public health. Combination therapy is a strategy for the treatment of antibiotic‐resistant infections.
Hossein Kazemian +4 more
doaj +1 more source
Combination of HDAC and FYN inhibitors in synovial sarcoma treatment
The SS18-SSX fusion protein is an oncogenic driver in synovial sarcoma. At the molecular level, SS18-SSX functions as both an activator and a repressor to coordinate transcription of different genes responsible for tumorigenesis.
Kyra Parker +6 more
doaj +1 more source
The Acquired Vulnerability Caused by CDK4/6 Inhibition Promotes Drug Synergism Between Oxaliplatin and Palbociclib in Cholangiocarcinoma. [PDF]
Suppramote O +12 more
europepmc +1 more source

