Results 11 to 20 of about 1,952,521 (307)

Omadacycline Potentiates Clarithromycin Activity Against Mycobacterium abscessus

open access: yesFrontiers in Pharmacology, 2021
Mycobacterium abscessus is a difficult respiratory pathogen to treat, when compared to other nontuberculus mycobacteria (NTM), due to its drug resistance.
Bui Thi Bich Hanh   +7 more
doaj   +1 more source

Basic principles of combination therapy: focus on drug-drug interaction

open access: yesКардиоваскулярная терапия и профилактика, 2021
The article is devoted to the issue of drug interactions in the combination regimens. Today, when drug therapy is the first-line approach for patients with noncommunicable diseases, and the world population ageing leads to an increase in the number of ...
S. Yu. Martsevich   +2 more
doaj   +1 more source

Independent Drug Action in Combination Therapy: Implications for Precision Oncology

open access: yesCancer Discovery, 2022
Combination therapies are superior to monotherapy for many cancers. This advantage was historically ascribed to the ability of combinations to address tumor heterogeneity, but synergistic interaction is now a common explanation as well as a design ...
D. Plana, A. Palmer, P. Sorger
semanticscholar   +1 more source

Potential drug interactions in adults living in the Brazilian Amazon: A population-based case-control study, 2019

open access: yesExploratory Research in Clinical and Social Pharmacy, 2021
Background: Drug interactions are important causes of adverse events. Assessments of pharmacological interactions outside healthcare services settings are scarce. Objective: To assess the frequency and factors associated with these potential interactions
Tayanny Margarida Menezes Almeida Biase   +2 more
doaj   +1 more source

Functional ligands for improving anticancer drug therapy: current status and applications to drug delivery systems

open access: yesDrug Delivery, 2022
Conventional chemotherapy lacking target selectivity often leads to severe side effects, limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both selective drug release and efficient intracellular uptake at the target ...
Rajiv Bajracharya   +11 more
semanticscholar   +1 more source

Photodynamic‐Chemodynamic Cascade Reactions for Efficient Drug Delivery and Enhanced Combination Therapy

open access: yesAdvancement of science, 2021
Nanomedicines with photodynamic therapy and reactive oxygen species (ROS)‐triggered drug release capabilities are promising for cancer therapy. However, most of the nanomedicines based on ROS‐responsive nanocarriers still suffer from serious ROS ...
Sheng Wang   +8 more
semanticscholar   +1 more source

Amphiphilic photosensitizer polymer as a nanocarrier of cytotoxic molecule for carrier‐free combination therapy

open access: yesMedComm – Biomaterials and Applications, 2023
Various nanocarriers have been explored to deliver drugs for combination therapy. However, most nanocarriers are composed of inert materials without contribution for improving the cancer therapeutic effect.
Jingqi Xin   +3 more
doaj   +1 more source

Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study [PDF]

open access: yesDiabetes & Metabolism Journal, 2020
BackgroundThere is limited information regarding the optimal third-line therapy for managing type 2 diabetes mellitus (T2DM) that is inadequately controlled using dual combination therapy.
Jeong Mi Kim   +12 more
doaj   +1 more source

Tools to develop antibiotic combinations that target drug tolerance in Mycobacterium tuberculosis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Combination therapy is necessary to treat tuberculosis to decrease the rate of disease relapse and prevent the acquisition of drug resistance, and shorter regimens are urgently needed.
Talia Greenstein   +5 more
doaj   +1 more source

Nonalcoholic Fatty Liver Disease: A Drug Revolution Is Coming [PDF]

open access: yesDiabetes & Metabolism Journal, 2020
The worldwide prevalence of non-alcoholic fatty liver disease is around 25%, and that of nonalcoholic steatohepatitis (NASH) ranges from 1.5% to 6.45%.
Soung Won Jeong
doaj   +1 more source

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