Results 21 to 30 of about 6,853,200 (317)

High Drug-Loading Nanomedicines for Tumor Chemo–Photo Combination Therapy: Advances and Perspectives

Pharmaceutics, 2022
The combination of phototherapy and chemotherapy (chemo–photo combination therapy) is an excellent attempt for tumor treatment. The key requirement of this technology is the high drug-loading nanomedicines, which can load either chemotherapy drugs or ...
Ya Wang, Yujie Zhang, Xiaojiang Zhang, Zhe Zhang, Junjun She, Daocheng Wu, Wei Gao   +6 more
doaj   +1 more source

Combination Drug Therapy for Cryptosporidiosis in AIDS [PDF]

The Journal of Infectious Diseases, 1998
Aside from effective antiretroviral therapy, there is no consistently effective antiparasitic therapy for cryptosporidiosis in AIDS. The purpose of this study was to assess safety, efficacy, and durability of combination therapy with paromomycin and azithromycin for chronic cryptosporidiosis. Patients with AIDS, chronic cryptosporidiosis, and < 100 CD4
N H, Smith, S, Cron, L M, Valdez, C L, Chappell, A C, White   +4 more
openaire   +2 more sources

A comparison between abacavir and efavirenz as the third drug used in combination with a background therapy regimen of 2 nucleoside reverse-transcriptase inhibitors in patients with initially suppressed viral loads [PDF]

, 2006
Background. Our objective was to compare the rate of viral rebound and therapy failure in patients receiving abacavir or efavirenz as the third drug ( in addition to 2 non-abacavir nucleosides) in combination antiretroviral therapy ( cART) and to compare
Phillips, AN, L. Sighinolfi, D'ARMINIO MONFORTE A, R. Cauda, MOIOLI MC, Monforte, AD, COZZI-LEPRI A, DI GIAMBENEDETTO S, M. Mena, Sighinolfi, L, SIGHINOLFI L, A. Cozzi Lepri, Lichtner, M, ICoNA Study Group, Arlotti, M, M. Lichtner, Bongiovanni, M, Mena, M, M. Arlotti, UCSC Roma HIV Cohort Study Group, CAUDA R, A. N. Phillips, De Luca, A, Di Giambenedetto, S, Cozzi-Lepri, A, DE LUCA A, BONGIOVANNI M, PHILLIPS AN, UCSC-Roma HIV Cohort Study Grp, Narciso, P, Cauda, R, IMIT Study Grp, IMIT Study Group, A. De Luca, ICoNA Study Grp, MENA M, ARLOTTI M, NARCISO P, LICHTNER M, M. C. Moioli, Moioli, MC, S. Di Giambenedetto, P. Narciso, M. Bongiovanni, A. d’Arminio Monforte   +44 more
core   +1 more source

Recent Advances in Curcumin-Based Combination Nanomedicines for Cancer Therapy

Journal of Functional Biomaterials, 2023
Standard cancer chemotherapeutics often produce significant adverse effects and eventually lose their effectiveness due to the emergence of resistance mechanisms.
Amir R. Afshari, Mehdi Sanati, Prashant Kesharwani, Amirhossein Sahebkar   +3 more
doaj   +1 more source

Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]

, 2014
This work was supported by grants from Breakthrough Breast Cancer and Scottish Funding Council (SRDG), and personal support to Alexey Goltsov from Scottish Informatics and Computer Science Alliance (SICSA) and to James Bown from The Northwood Trust.Drug ...
Bown, James, Goltsov, Alexey, Gregory Goltsov, Harrison, David J, Bown, J., Goltsov, Gregory, Simon P. Langdon, James eBown, Langdon, Simon P., Bown, James L., Langdon, S.P., Goltsov, G., Alexey eGoltsov, David eHarrison, Gregory eGoltsov, Alexey Goltsov, Harrison, D.J., Goltsov, A., Langdon, Simon P, David J. Harrison, Simon eLangdon, James Bown, Harrison, David J.   +22 more
core   +1 more source

Rational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric malaria cases? [PDF]

, 2011
Artemisinin-based combination therapy is exerting novel selective pressure upon populations of Plasmodium falciparum across Africa. Levels of resistance to non-artemisinin partner drugs differ among parasite populations, and so the artemisinins are not ...
Mackinnon, Margaret J, Sutherland, CJ, Ranford-Cartwright, L, COLIN J. SUTHERLAND, MARGARET J. MACKINNON, Babiker, H., MacKinnon, M.J., El Sayed, BB, HAMZA BABIKER, Sutherland, Colin J, Ranford-Cartwright, Lisa, Mackinnon, Margaret, El Sayed, Badria Babiker, Sayed, B.B., Sutherland, C.J., Babiker, H, Ranford-Cartwright, L.C., LISA RANFORD-CARTWRIGHT, BADRIA BABIKER EL SAYED, Babiker, Hamza   +19 more
core   +1 more source

Are Tanzanian patients attending public facilities or private retailers more likely to adhere to artemisinin-based combination therapy? [PDF]

, 2015
BACKGROUND: Artemisinin combination therapy (ACT) is first-line treatment for malaria in most endemic countries and is increasingly available in the private sector. Most studies on ACT adherence have been conducted in the public sector, with minimal data
Catherine Goodman, Schellenberg, David, Kalolella, Admirabilis, Katia Bruxvoort, Bruxvoort, Katia, Matthew Cairns, Festo, Charles, Charles Festo, David Schellenberg, Peter Lyaruu, S Kachur, Goodman, Catherine, Kenani, Mitya, Kachur, S Patrick, Lyaruu, Peter, Admirabilis Kalolella, Mitya Kenani, Cairns, Matthew   +17 more
core   +1 more source

Priority Setting for the Implementation of Artemisinin-Based Combination Therapy Policy in Tanzania: Evaluation Against the Accountability for Reasonableness Framework. [PDF]

, 2012
\ud Priority setting for artemisinin-based antimalarial drugs has become an integral part of malaria treatment policy change in malaria-endemic countries. Although these drugs are more efficacious, they are also more costly than the failing drugs.
Mori Amani, Kaale, E.A., Mori, Amani Thomas, Amani Thomas Mori, Kaale, Eliangiringa Amos, Mori, A.T., Kaale Eliangiringa, Eliangiringa Amos Kaale   +7 more
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Drug Combinations in Breast Cancer Therapy [PDF]

Pharmaceutical Nanotechnology, 2019
Breast cancer therapy involves a multidisciplinary approach comprising surgery, radiotherapy, neoadjuvant and adjuvant therapy. Effective therapy of breast cancer requires maximum therapeutic efficacy, with minimal undesirable effects to ensure a good quality of life for patients.
Fisusi, Funmilola A., Akala, Emmanuel O.
openaire   +2 more sources

Variable impact on mortality of AIDS‐Defining events diagnosed during combination antiretroviral therapy: Not All AIDS‐defining conditions are created equal [PDF]

, 2009
Background The extent to which mortality differs following individual acquired immunodeficiency syndrome (AIDS)–defining events (ADEs) has not been assessed among patients initiating combination antiretroviral therapy.
Justice, Amy, Saaq, M., Crevel, R. van, Sterne, Jonathan A C, Justice A., Reiss, Peter, HARRIS R, R. Harris, Staszewski, S., Mocroft, A., Sabin, Caroline, G. Fatkenheuer, D'Arminio-Monforte, A., Fatkenheuer, G., Egger, M., Phillips, E., Groot, R. de, Harris, Ross, Gill J., KITAHATA M, S. Grabar, Sterne, J.A., F. Bonnet, May, M., Post, F., CASABONA J, A. Justice, Ven, A.J.A.M. van der, Mocroft, A, Casabona J., H. Furrer, J. Casabona, M. Egger, Reiss P., Antiretroviral Therapy Cohort Collaboration, Casabona, Jordi, D'ARMINIO MONFORTE A, FATKENHEUER G, STERNE JA, De Wit, Stéphane, Kitahata, Mari, Furrer H., d'Arminio Monforte, Antonella, Bonnet, F., C. Sabin, Sterne, Jonathan A. C., MONTRONI, MARIA, MAY M, SAAG M., Furrer, H., A. Mocroft, Staszewski, Schlomo, Justice, Amy C, Justice, A., MINOLI, LORENZO, Reiss, P., Sabin C., MANCUSO, Salvatrice, Antiretroviral Therapy Cohort Collaboration Mocroft A., Saag, Michael, Saag, M., J. Gill, Keuter, M., Warris, A., Hogg R., Staszewxski S., Sterne J.A., Clumeck, Nathan, S. Staszewski, Casabona, J., P. Reiss, Bonnef, VULLO, Vincenzo, Kitahata, M., Mocroft, Amanda, Furrer, Hansjakob, Koopmans †, P.P., Gill, J., Gill, John, Bonnet, Fabrice, GRABAR S, REISS P, ?, ?, Hogg, Robert, M. Kitahata, CIARDI, Maria Rosa, et al., EGGER M, Niesters, Bert, Egger, Matthias, Harris R., Fatkenheuer G., May, Margaret T, JUSTICE A, HOGG R, May M., Grabar, Sophie, Fatkenheuer, Gerd, ANTIRETROVIRAL THERAPY COHORT COLLABORATION ART CC, May, Margaret, Egger M., d'Arminio Monforte A., M. May, GILL J, Grabar S., D'Arminio Monforte, A., Grabar, S., A. d'Arminio Monforte, Kitahata M., SABIN C, R. Hogg, Harris, R., Sabin, C., Post, Frank, J. A. Sterne, STASZEWSKI S, FURRER H, Gyssens, I.C.J., MOCROFT A, M. Saag, Hogg, R., BONNET F   +121 more
core   +3 more sources