Results 11 to 20 of about 6,853,200 (317)

Nonalcoholic Fatty Liver Disease: A Drug Revolution Is Coming [PDF]

Diabetes & Metabolism Journal, 2020
The worldwide prevalence of non-alcoholic fatty liver disease is around 25%, and that of nonalcoholic steatohepatitis (NASH) ranges from 1.5% to 6.45%.
Soung Won Jeong
doaj   +1 more source

Metabolic Derangements with Anticonvulsants in Children with Generalised Tonic-clonic Epilepsy: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Epilepsy is one of the most prevalent noncommunicable neurologic conditions, accounting for significant disability and mortality. The effects of Antiepileptic Drugs (AEDs) on total cholesterol, triglycerides, High-Density Lipoprotein ...
Jyoti Sharma, Savita Verma, Himani Deswal, Jayashankar Kaushik   +3 more
doaj   +1 more source

AtriplaR/anti-TB Combination in TB/HIV Patients. Drug in Focus. [PDF]

, 2011
Co-administration of anti-tuberculosis and antiretroviral therapy is often inevitable in high-burden countries where tuberculosis is the most common opportunistic infection associated with HIV/AIDS. Concurrent use of rifampicin and several antiretroviral
Semvua Hadija H, Kibiki, Gibson S, Hadija H Semvua, Gibson S Kibiki, Semvua, Hadija H, Kibiki Gibson S   +5 more
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Overcoming the challenges of drug resistance through combination drug delivery approach

, 2022
Anticancer and antimicrobial drug resistances are the most important problems that decrease the overall success of drug treatment in the clinic. The combination of two or more different kinds of drugs in clinical practice has been generally accepted as a
Tonbul, Hayrettin, Çapan, Yılmaz, Şahin, Adem   +2 more
core   +1 more source

Systems analysis of drug-induced receptor tyrosine kinase reprogramming following targeted mono- and combination anti-cancer therapy [PDF]

, 2014
The receptor tyrosine kinases (RTKs) are key drivers of cancer progression and targets for drug therapy. A major challenge in anti-RTK treatment is the dependence of drug effectiveness on co-expression of multiple RTKs which defines resistance to single ...
Goltsov, Alexey, Stylianos Kyriakidis, Hilal Khalil, Simon P. Langdon, Harrison, David James, Langdon, Simon P., Bown, James L., Khalil, Hilal S., Simon Langdon, Tero Soininen, Khalil, Hilal S, Soininen, Tero, Alexey Goltsov, Huizhong Hu, David J. Harrison, Bown, James, David Harrison, Deeni, Yusuf, Harrison, David J, Kyriakidis, Stylianos, Hu, Huizhong, Deeni, Yusuf Y.; id_orcid, Yusuf Deeni, Hilal S. Khalil, Langdon, Simon P, James Bown, Harrison, David J.   +26 more
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Combination Drug Therapy in Refractory Epilepsy

Pediatric Neurology Briefs, 2012
Researchers from University of Washington, Seattle, WA analyzed the treatment records from 148 developmentally disabled adults with refractory epilepsy cared for in 2 state-run institutions.
J Gordon Millichap
doaj   +1 more source

The costs of introducing artemisinin-based combination therapy: evidence from district-wide implementation in rural Tanzania. [PDF]

, 2008
BACKGROUND\ud \ud The development of antimalarial drug resistance has led to increasing calls for the introduction of artemisinin-based combination therapy (ACT).
Goodman Catherine A, Mulligan Jo, Abdulla, Salim, Bloland, Peter, McHomvu, Naiman, Mills, Anne, Mills Anne, Mchomvu Naiman, Munkondya John S, Njau Joseph D, Abdulla Salim, Munkondya, John S, Bloland Peter, Kachur, S Patrick, Njau, Joseph D, Goodman, Catherine A, Kachur S Patrick, Mulligan, Jo   +17 more
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The use of mono- and combination drug therapy in men and women with lower urinary tract symptoms (LUTS) in the UK: a retrospective observational study

BMC Urology, 2021
Background Combination drug therapy for lower urinary tract symptoms (LUTS) is beneficial to selected patients and recommended by guidelines. Patterns of real-world LUTS drug use, especially combination drug therapy, have not been studied extensively ...
Mahmood Ali, Margarita Landeira, Patrick J. O. Covernton, Nurul Choudhury, Ashley Jaggi, Francis Fatoye, Rob van Maanen   +6 more
doaj   +1 more source

Experimental Drugs and Combination Therapy

Immunobiology, 1994
The worldwide increase in tuberculosis, the additional problem of increasing multiple drug resistance (MDR) and the primary resistance of Mycobacterium avium requires new strategies in drug development and in therapy. The reason for development of MDR is manifold. One important factor is the change in cell wall construction which limits the penetration
J K, Seydel, K J, Schaper, S, Rüsch-Gerdes   +2 more
openaire   +2 more sources

Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda. [PDF]

, 2005
BACKGROUND: Drug resistance in Plasmodium falciparum poses a major threat to malaria control. Combination antimalarial therapy including artemisinins has been advocated recently to improve efficacy and limit the spread of resistance, but artemisinins are
Albert Kilian, Sarah G Staedke (18026), Grant Dorsey, Yeka Adoke, Dorsey Grant, Kilian Albert, Kristin Banek (18020), Rosenthal Philip J, Grant Dorsey (18025), Moses R Kamya (18018), Reingold, Arthur, Nathan Bakyaita, Banek, Kristin, Staedke, Sarah G, Rosenthal, Philip J., Arthur Reingold (275222), Philip J Rosenthal (18023), Samuel L Nsobya (275219), Banek Kristin, Fred Wabwire-Mangen (18024), Kamya, Moses.R, Albert Kilian (275220), Madeline Slater (275221), Kamya Moses R, Arthur Reingold, Wabwire-Mangen Fred, Fred Wabwire-Mangen, Wabwire-Mangen, Fred, Staedke Sarah G, Sarah G Staedke, Moses R Kamya, Kristin Banek, Kironde, Fred, Slater, Madeline, Dorsey, Grant, Nsobya, Samuel L., Reingold Arthur, Ambrose Talisuna, Fred Kironde (44975), Kilian, Albert, Talisuna, Ambrose, Bakyaita, Nathan, Fred Kironde, Madeline Slater, Rosenthal, Philip J, Nsobya, Samuel L, Ambrose Talisuna (18019), Slater Madeline, Yeka, Adoke, Nsobya Samuel L, Bakyaita Nathan, Kironde Fred, Philip J Rosenthal, Talisuna Ambrose, Adoke Yeka, Samuel L Nsobya, Kamya, Moses R, Staedke, Sarah G., Nathan Bakyaita (18021), Adoke Yeka (18017)   +59 more
core   +2 more sources