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Understanding and targeting resistance mechanisms in cancer
MedComm, 2023 Resistance to cancer therapies has been a commonly observed phenomenon in clinical practice, which is one of the major causes of treatment failure and poor patient survival. The reduced responsiveness of cancer cells is a multifaceted phenomenon that can
Zi‐Ning Lei +6 more
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Metabolic Derangements with Anticonvulsants in Children with Generalised Tonic-clonic Epilepsy: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Epilepsy is one of the most prevalent noncommunicable neurologic conditions, accounting for significant disability and mortality. The effects of Antiepileptic Drugs (AEDs) on total cholesterol, triglycerides, High-Density Lipoprotein ...
Jyoti Sharma +3 more
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BMC Urology, 2021 Background Combination drug therapy for lower urinary tract symptoms (LUTS) is beneficial to selected patients and recommended by guidelines. Patterns of real-world LUTS drug use, especially combination drug therapy, have not been studied extensively ...
Mahmood Ali +6 more
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Drug Combinations in Breast Cancer Therapy [PDF]
Pharmaceutical Nanotechnology, 2019 Breast cancer therapy involves a multidisciplinary approach comprising surgery, radiotherapy, neoadjuvant and adjuvant therapy. Effective therapy of breast cancer requires maximum therapeutic efficacy, with minimal undesirable effects to ensure a good quality of life for patients.
Funmilola A. Fisusi, Emmanuel O. Akala
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Machine learning approaches for drug combination therapies [PDF]
Briefings in Bioinformatics, 2021 AbstractDrug combination therapy is a promising strategy to treat complex diseases such as cancer and infectious diseases. However, current knowledge of drug combination therapies, especially in cancer patients, is limited because of adverse drug effects, toxicity and cell line heterogeneity. Screening new drug combinations requires substantial efforts
Betul Guvenc Paltun +7 more
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Open Journal of Psychiatry and Allied Sciences, 2016 Objective: To study the prescribing pattern of antipsychotic drugs in the outpatient department of psychiatry in Silchar Medical College and Hospital (SMCH) of Assam.
Pinaki Chakravarty +2 more
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High Drug-Loading Nanomedicines for Tumor Chemo–Photo Combination Therapy: Advances and Perspectives
Pharmaceutics, 2022 The combination of phototherapy and chemotherapy (chemo–photo combination therapy) is an excellent attempt for tumor treatment. The key requirement of this technology is the high drug-loading nanomedicines, which can load either chemotherapy drugs or ...
Ya Wang +6 more
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Disseminated Rhodococcus equi infection in a patient with Hodgkin’s lymphoma [PDF]
Vojnosanitetski Pregled, 2014 Introduction. Rhodococcus (R) equi is an opportunistic, uncommon human pathogen that causes mainly infection in immunocompromised hosts. The disease is usually presented as subacute pneumonia that is mostly cavitary and sometimes bacteremic ...
Mikić Dragan +3 more
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Recent Advances in Curcumin-Based Combination Nanomedicines for Cancer Therapy
Journal of Functional Biomaterials, 2023 Standard cancer chemotherapeutics often produce significant adverse effects and eventually lose their effectiveness due to the emergence of resistance mechanisms.
Amir R. Afshari +3 more
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Multi Drug Therapy- Combination of Structural Inhibitors to Eradicate Leprosy
, 2015 : Being persistant infection, caused by Mycobacterium leprae, Leprosy is affecting about 50,000 annually. It affects Schwann cells (the glial cells of peripheral nervous system) and macrophages.
V. Kashyap, A. Pandey, S. Tripathi
semanticscholar +1 more source