Results 191 to 200 of about 5,954,250 (317)

Correction to 'The First MASH Drug Therapy on the Horizon: Current Perspectives of Resmetirom'. [PDF]

Liver Int
europepmc   +1 more source

Safe Practices in Intravenous Drug Therapy in Hospitalized Adult Patients: Scoping Review. [PDF]

Rev Bras Enferm
Rocha HDSD, Guedes MCC, Goulart MCEL, Góes FGB, Santos ASLD, Pereira-Ávila FMV.   +5 more
europepmc   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

QTc Interval Prolongation and Associated Drug Therapy in Hospitalized Older Adults. [PDF]

J Am Geriatr Soc
Fantin F, Fiorini S, Giani A, Giacobbe L, Zoico E, Trifirò G, Micciolo R, Zamboni M.   +7 more
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Photodynamic Therapy Combined with Anticancer Drug Therapy in the Treatment of Malignant Neoplasms. [PDF]

Cells
Reshetov I, Alyasova A, Shpileva O, Karalkin P, Efendiev K, Pominova D, Loschenov V, Ilyasova D, Agakina Y, Gilyadova A, Cheremisov V, Stetsiuk A, Mamedova A, Petrova A, Kozlova P, Rostislavova E, Sudarkina V, Abadzhyan D, Shiryaev A.   +18 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Risk Factors for Poor Neurological Outcomes at Discharge in Tuberculous Meningitis: Disease Severity, Host Factors, and Drug Therapy. [PDF]

Trop Med Infect Dis
Yu Y, Liu H, Yang H, Ye D, Xia L, Ma X, Wang J, Sun Y, Li F, Chen Y.   +9 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Review of Polymer Drug Therapy for Cancer Driven by Artificial Intelligence. [PDF]

Polymers (Basel)
Zheng J, Ye Y.
europepmc   +1 more source