Results 181 to 190 of about 411,089 (301)

Water‐Compatible SuFEx‐Active Diazonium Linchpin Platform for Rapid Modular Diversification and On‐DNA Functionalization

Advanced Functional Materials, EarlyView.
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong, Dong Hyeon Kim, Yujin Lim, Yongseok Kwon, Sangkyu Lee, Han Yong Bae   +5 more
wiley   +1 more source

p53 mutations define the chromatin landscape to confer drug tolerance in pancreatic cancer. [PDF]

Mol Oncol, 2022
Zampieri C, Panatta E, Corbo V, Mauriello A, Melino G, Amelio I.   +5 more
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Variability in intrinsic drug tolerance in <i>Mycobacterium tuberculosis</i> corresponds with phylogenetic lineage. [PDF]

Antimicrob Agents Chemother
March VFA, Zwyer M, Loiseau C, Brites D, Goig GA, Bouaouina S, Doetsch A, Reinhard M, Kalkan S, Gagneux S, Borrell S.   +10 more
europepmc   +1 more source

A previously uncharacterized gene, PA2146, contributes to biofilm formation and drug tolerance across the ɣ-Proteobacteria. [PDF]

NPJ Biofilms Microbiomes, 2022
Kaleta MF, Petrova OE, Zampaloni C, Garcia-Alcalde F, Parker M, Sauer K.   +5 more
europepmc   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Expression patterns of core metabolic genes and elevated intracellular ROS confer drug tolerance in <i>Staphylococcus aureus</i>. [PDF]

Microbiol Spectr
Liu J, Li Y, Liu H, Yan S, Jia H, Yang Y, Hu W, Wang J, Li W, Xue H, Zhao X, Li L, Liu P.   +12 more
europepmc   +1 more source

Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in Candida albicans. [PDF]

mBio, 2021
Yang F, Gritsenko V, Slor Futterman Y, Gao L, Zhen C, Lu H, Jiang YY, Berman J.   +7 more
europepmc   +1 more source

Interstitium‐Mimicking Porous Alveolar Membranes Enable Physiologic Aerosol Transport and Distinct Acute‐Chronic Lung Injury Responses

Advanced Functional Materials, EarlyView.
An interstitium‐mimicking membrane combines three‐dimensional alveolar geometry, high pore interconnectivity, and mechanical compliance to overcome transport limitations of conventional lung‐on‐chip barriers. The resulting platform supports physiologic aerosol transport, quantitative analysis of cross‐barrier particle movement, and reveals divergent ...
Jae‐Won Choi, Sheng Zhang, Abbas Jalili, August Kohls, Woo‐Youl Maeng, Sikandar Azam, Wu Liu, Barbie Varghese, Yixin Zhao, Xi Ren, Shimin Liu, Si‐Yang Zheng   +11 more
wiley   +1 more source