Results 191 to 200 of about 411,089 (301)

Nucleoid-associated protein HU constrains transcription elongation to influence cellular functions, virulence, and drug tolerance in Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Santoshi M, Anand C, Hussain M, Rajmani RS, Ghosh S, Nagaraja V.   +5 more
europepmc   +1 more source

Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis. [PDF]

PLoS Pathog, 2022
Martini MC, Hicks ND, Xiao J, Alonso MN, Barbier T, Sixsmith J, Fortune SM, Shell SS.   +7 more
europepmc   +1 more source

From Photoalignment to Structured Light: Liquid Crystal Platforms for Beam Shaping and Complex Wavefronts

Advanced Functional Materials, EarlyView.
Photoaligned and photopatterned liquid crystal platforms provide programmable control of optical phase, polarization, and spin‐orbit interactions, enabling compact generation of structured light and complex wavefronts. This review highlights how tailored molecular orientations transform simple beams into designed optical fields, opening versatile ...
Le Zhou, Tingjun Zhong, Sijie Liu, Pouya Nosratkhah, Ke Xu, Yuzhen Zhao, Kristiaan Neyts   +6 more
wiley   +1 more source

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance. [PDF]

Nat Microbiol, 2022
Yu JSL, Correia-Melo C, Zorrilla F, Herrera-Dominguez L, Wu MY, Hartl J, Campbell K, Blasche S, Kreidl M, Egger AS, Messner CB, Demichev V, Freiwald A, Mülleder M, Howell M, Berman J, Patil KR, Alam MT, Ralser M.   +18 more
europepmc   +1 more source

3D‐Printable, Biodegradable, and Conductive/Piezoionic Hydrogel ‘E‐Skin’ With Robust Antibacterial Properties for Wound Healing and Wireless Human‐Machine Interface Sensing

Advanced Functional Materials, EarlyView.
A multifunctional MXene‐integrated GelMA/alginate hydrogel reinforced with TEMPO‐modified nanocellulose is engineered via dynamic covalent, ionic, and hydrogen bonding. The resulting piezoelectric, adhesive, antimicrobial, and 3D‐printable patch enables motion sensing and accelerates wound healing by promoting keratinocyte migration and collagen ...
Myoungjoon Jeon, Sayan Deb Dutta, Md. Moniruzzaman, Jeong Man An, Youjin Seol, Gyuhan Son, Sung Ha Jo, Hyun Chang Jung, Beom‐Soo Shin, Jongsung Kim, Yong‐kyu Lee, Ki‐Taek Lim   +11 more
wiley   +1 more source

Incorporation of macrophage immune stresses into an intracellular assay of drug tolerance in <i>Mycobacterium tuberculosis</i>. [PDF]

Antimicrob Agents Chemother
Kirubakar G, Johnston L, Nae Rin Lee B, Russell DG, Simwela NV.   +4 more
europepmc   +1 more source

Drug Tolerance to EGFR Tyrosine Kinase Inhibitors in Lung Cancers with EGFR Mutations. [PDF]

Cells, 2021
Suda K, Mitsudomi T.
europepmc   +1 more source

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

Advanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar, Deeksha Kumaresh, Eduardo Nombera Bueno, Mae Pryor, Paula T. Hammond   +4 more
wiley   +1 more source

Improving sensitivity and drug tolerance of assays for neutralizing anti-drug antibodies to semaglutide and native GLP-1. [PDF]

Bioanalysis
Videbæk N, Jørgensen L, de Lemos Rieper C, Hummelshøj L, Petersen SS, Wøldike DBC, Andresen LO.   +6 more
europepmc   +1 more source

Polarization Sensitivity of Chiral Manganese Halide Scintillators Enables High‐Resolution X‐Ray Imaging

Advanced Functional Materials, EarlyView.
Highly luminescent chiral manganese halide crystals are synthesized using chiral ligands, and they exhibit dissymmetry factors up to 1.4 × 10−2 and show X‐ray detection scintillation capability with a light yield of 43 380 photons/MeV and a low detection limit of 0.05198 µGyair·s−1.
Yue Han, Jun'an Lai, Peng He, Wenxia Zhang, Xirong Ke, Shengsi Liu, Kang An, Xiao‐Fang Jiang, Lakshminarayana Polavarapu, Xiaosheng Tang   +9 more
wiley   +1 more source