Results 221 to 230 of about 132,064 (306)

Intracellular Pharmacokinetics of Antidiabetic Drugs: A Focused Narrative Review of Subcellular Distribution (2015-2025). [PDF]

Diseases
Bafail DA.
europepmc   +1 more source

Trackable Tolerogenic Macrophages Integrate PD‐L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation

Advanced Science, EarlyView.
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang, Yuan Song, Yuji Xie, Junmin Zhang, Jing Liu, Wenyuan Wang, Ying Xu, Wenqian Wu, Wuqi Zhou, Qiaofeng Jin, Jing Wang, Yali Yang, Li Zhang, Tang Gao, Mingxing Xie   +14 more
wiley   +1 more source

Improving Proteostasis of Trafficking-Deficient GABA_A Receptor Variants by Activating IRE1. [PDF]

ACS Chem Neurosci
Fu X, Wang YJ, Lee K, Ahn LY, Chen X, Harvey BT, Wang M, Seibert H, Zhang PP, Guerrero A, Schaffer AE, Richards CI, Wiseman RL, Kelly JW, Mu TW.   +14 more
europepmc   +1 more source

Coacervate‐Mediated Lysosome‐Targeting Antibody Delivery for Protein Degradation

Advanced Science, EarlyView.
Targeting coacervates to the lysosome in the cytoplasm is a challenge. Here, we convert a tetrapeptide into lysosome‐targeting, membrane‐translocating coacervates. The lysosome‐sorting peptide coacervates facilitate coacervate‐mediated delivery of antibody antigen complexes and a PROTAC compound to the lysosome for the targeted degradation of cancer ...
Dingdong Yuan, Yishu Bao, Zhiyi Xu, Zhong Zheng, Yongxu Han, Kai Cheng, Yuan‐Di Zhao, Jiang Xia   +7 more
wiley   +1 more source

Editorial: Reviews and advances on the role of membrane trafficking in cancer. [PDF]

Front Cell Dev Biol
Lamaze C, Gasman S, MacDonald E.
europepmc   +1 more source

Drug Trafficking Deterrence Signs and Ohio Schools: A Survey of Ohio Principals

Peter Leasure
openalex   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

The threat from Transnational Crime in Southeast Asia: Drug Trafficking, Human Smuggling and Trafficking and sea piracy.

Revista UNISCI, 2003
Ralf Emmers
doaj  

Recent Advances in Proximity Labeling-Based Subcellular Proteomic Mapping. [PDF]

Mol Cell Proteomics
Wang G, Liu J, Sun X, Qin W, Han S, Zou P.   +5 more
europepmc   +1 more source

The process of desecuritization of drug trafficking in Unasur

, 2014
Mariana Preta Oliveira de Lyra
openalex   +1 more source