Results 41 to 50 of about 132,064 (306)
Nuevas geografías del narcotráfico. La novela gallega sobre el tráfico de drogas
Confluenze, 2020 The drug trafficking fiction is expanding throughout a new geography. The almost recent appearance of Galician novels about cocaine trafficking in Northern Spain and the connections between the local capos with Colombian and Mexican cartels enriches the ...
Felipe Oliver
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BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Siyar JournalThis study describes UNODC's efforts to prevent the circulation of synthetic drugs in Southeast Asia. This study was conducted to determine what efforts UNODC, as an international organization, has made to address the high number of synthetic drug ...
Muhammad Rizki Dwi Nurdiansyah +1 more
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Social Sciences, 2023 The drug/violence relationship has been a recurrent topic of interest in criminology and sociology. This interest began with the crack epidemic in the 1980s and continues due to the consolidation and functioning of the cocaine markets of Latin American ...
Williams Gilberto Jiménez-García +2 more
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FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Challenges and Strategies of Drug Trafficking in the Islamic Republic of Iran: A Qualitative Study Based on Analysis of Online News Media [PDF]
, 2023 Nourolhoda Fakhrzad +2 more
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FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
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War Zone Acapulco: Urban Drug Trafficking in the Americas
Contexto InternacionalAcapulco epitomises the (in)security of urban zones in the Americas whose geographical, political and economic divisions are exacerbated by the political economy and geopolitics of drug trafficking, as well as by militarised attempts to fight it. Various
Thiago Rodrigues +3 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source