Results 71 to 80 of about 4,204,718 (353)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
KERJASAMA INDONESIA- MALAYSIA DALAM MENANGANI PEREDARAN NARKOBA DI PERBATASAN
Dinamika Global, 2020 Indonesia and Malaysia have close ties especially in their land borders, making it easier to access buying and selling that occurs between communities on the border. Especially in trade to drug trafficking that occurs in border areas such as the Entikong-
Ade Priangani +2 more
doaj +1 more source
Courts Have Gone Overboard in Applying the Maritime Drug Law Enforcement Act [PDF]
, 2018 The Maritime Drug Law Enforcement Act (MDLEA), enacted through Congress’s power to “define and punish . . . Felonies Committed on the high Seas,” prosecutes individuals for drug trafficking “on board” vessels.
Aquila, Elaina
core +1 more source
, 2018 While Mexico is widely considered as an example of consolidated statehood, the deepening of drug-related violence and insecurity has corroborated the existence and expansion of ‘dark spaces’ governed by coalitions of state and non-state actors driven by ...
W. Pansters
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
A spatio-temporal analysis of forest loss related to cocaine trafficking in Central America
Environmental Research Letters, 2017 A growing body of evidence suggests that criminal activities associated with drug trafficking networks are a progressively important driver of forest loss in Central America. However, the scale at which drug trafficking represents a driver of forest loss
Steven E Sesnie +7 more
doaj +1 more source
Membrane Trafficking and Subcellular Drug Targeting Pathways
Frontiers in Pharmacology, 2020 The movement of micro and macro molecules into and within a cell significantly governs several of their pharmacokinetic and pharmacodynamic parameters, thus regulating the cellular response to exogenous and endogenous stimuli.
Ajay Kumar +3 more
doaj +1 more source
Narco Trafficking, Corruption, and Perpetuated Violence in Guatemala [PDF]
, 2015 : Narco-trafficking and Perpetuated Violence in Guatemala Over the years drug cartels have made their way into Guatemala through their borders. Drug trafficking is the main reason why the border between Guatemala and Honduras is one of the most violent ...
Haque, Ima T
core +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Estimating the Size and Structure of the Underground Commercial Sex Economy in Eight Major U.S. Cities [PDF]
, 2014 The underground commercial sex economy (UCSE) generates millions of dollars annually, yet investigation and data collection remain under resourced. Our study aimed to unveil the scale of the UCSE in eight major US cities.
Bilal Khan +7 more
core +1 more source