Results 261 to 270 of about 2,100,066 (288)

Importance of Drug Transporters in Pharmacokinetics and Drug Safety

Toxicology Mechanisms and Methods, 2008
ABSTRACT The exact role of transporters in the absorption, distribution, and excretion (ADE) of drugs is still being elucidated; however, current evidence suggests that their role in these processes may be significant. In this review, the role of transporters in the ADE, pharmacology, toxicology, and clinical drug-drug interactions (DDIs) of drugs will
openaire   +2 more sources

Drug transport and transporters

2013
Roland J. Bainton, Evan D. Kharasch
openaire   +1 more source

Transporter-Mediated Drug-Drug Interactions and Their Significance

2019
Drug transporters are considered to be determinants of drug disposition and effects/toxicities by affecting the absorption, distribution, and excretion of drugs. Drug transporters are generally divided into solute carrier (SLC) family and ATP binding cassette (ABC) family.
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Antibody–Drug Conjugates: Smart Chemotherapy Delivery Across Tumor Histologies

Ca-A Cancer Journal for Clinicians, 2022
Shanu Modi, Javier Cortes, Jean-Charles Soria   +2 more
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Epigenetics in Toxicology and Drug Development

Medical Epigenetics, 2021
exaly  

Membrane Transporters in Drug Development

Nature Reviews Drug Discovery, 2010
Kathleen Giacomini, Sook Wah Yee
exaly  

What Do Drug Transporters Really Do?

Nature Reviews Drug Discovery, 2015
Sanjay Nigam
exaly  

Drug Transporters

Current Protocols in Toxicology, 2012
Julio C. Davila, Jose E. Manautou
openaire   +1 more source

Transporters in Drug Development: Advancing on the Critical Path

Nature Reviews Drug Discovery, 2010
Shiew-Mei Huang, Janet Woodcock
exaly  

Implications of Endogenous Roles of Transporters for Drug Discovery: Hitchhiking and Metabolite-Likeness

Nature Reviews Drug Discovery, 2016
Douglas Kell
exaly