Results 91 to 100 of about 817,567 (359)
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
THE CORRELATION BETWEEN POOR ORAL HYGIENE AND ORAL HEALTH-RELATED QUALITY OF LIFE AMONG DRUG USERS
Jurnal Berkala EpidemiologiBackground: The quality of life among drug users has become an increasingly important public health issue. One of the factors suspected to contribute to this is poor oral hygiene, which may result from reduced saliva production due to long-term use of ...
Riky Hamdani +2 more
doaj +1 more source
Polypharmacy Among Prescription Drug Users [PDF]
, 2017 Polypharmacy, i.e., the misuse of multiple prescription drugs or prescription medication with other substances, is highly problematic. Whether unintentional or deliberate, misuse of multiple drugs can lead to adverse effects including addiction; drug ...
Greene, Marion S., Omenka, Issac
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Market Analysis of Synthetic Drugs: Amphetamine-type Stimulants, New Psychoactive Substances [PDF]
, 2017 An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...
core
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Alcohol consumption in Colombian university students
Universidad y Salud, 2017 Introduction: Alcohol consumption is conceived as a public health problem. Given the significant prevalence of consumption and its negative consequences, it is necessary to contribute to the prevention from the identification of populations at risk, such
Sonia Betancourth Zambrano +2 more
doaj +1 more source
Hepatitis-C Virus Infection among Injecting Drug Users in Lahore, Pakistan: A Descriptive and Analytical Cross Sectional Study [PDF]
, 1969 Abdul Majeed Akhtar +4 more
openalex +1 more source
大学トレーニングセンターにおけるトレーニング器具の衛生状況について [PDF]
, 2018 University training center users include those attempting to improve their health. There are reports of a tendency of annual increase in the number of elderly people visiting fitness clubs.
田中 淳, 畑島 紀昭
core +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source