Results 81 to 90 of about 841,619 (362)
Reducing Infectious Diseases in the U.S.: Focus on HIV/AIDS and Hepatitis [PDF]
, 2009 Offers arguments for the efficacy of needle exchange programs in reducing infections among drug users and against the ban on using federal funds for such programs.
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User involvement and desired service developments in drug treatment: Service user and provider views [PDF]
, 2007 Aims - To investigate the existing level of user involvement at selected agencies, to examine views about user involvement from both service-user and provider perspectives and to compare desired service developments.
Beresford P +12 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
LEVELS OF PLASMA SOLUBLE CD14 IN HIV-INFECTED OPIATE USERS
Журнал инфектологии, 2018 Chronic immune activation is one of the main causes of HIV disease progression. Bacterial components passed to the bloodstream from the gut as a result of microbial translocation, are known to induce immune activation. Component of Gram-negative bacteria’
A. N. Kholodnaya +4 more
doaj +1 more source
Market Analysis of Plant-based Drugs C. The Cannabis Market [PDF]
, 2017 An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Findings from the DUMA program: impact of reduced methamphetamine supply on consumption of illicit drugs and alcohol [PDF]
This paper presents an analysis of retrospective self-reports from methamphetamine users (police detainees) on the impact that periods of reduced methamphetamine supply had on reported consumption of methamphetamine, alcohol and other illicit drugs ...
Sarah Coghlan, Susan Goldsmid
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Spatial mapping of hepatitis C prevalence in recent injecting drug users in contact with services. [PDF]
, 2011 In developed countries the majority of hepatitis C virus (HCV) infections occur in injecting drug users (IDUs) with prevalence in IDUs often high, but with wide geographical differences within countries.
A. MORONGIU +13 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source