The Association of Altered Gut Microbiota and Intestinal Mucosal Barrier Integrity in Mice With Heroin Dependence [PDF]
Frontiers in Nutrition, 2021 The gut microbiota is believed to play a significant role in psychological and gastrointestinal symptoms in heroin addicts. However, the underlying mechanism remains largely unknown. We show here that heroin addicts had a decrease in body mass index (BMI)
Jiqing Yang +26 more
doaj +3 more sources
Risk of Heroin Dependence in Newly Incident Heroin Users. [PDF]
JAMA Psychiatry, 2018 This study assesses data from the 2002 to 2016 US National Survey on Drug Use and Health data sets to determine the percentage of newly incident heroin users who became heroin dependent.
Santiago Rivera OJ +3 more
europepmc +4 more sources
Genome-Wide Association of Heroin Dependence in Han Chinese. [PDF]
PLoS ONE, 2016 Drug addiction is a costly and recurring healthcare problem, necessitating a need to understand risk factors and mechanisms of addiction, and to identify new biomarkers.
Gursharan Kalsi +12 more
doaj +3 more sources
GABRB2 Haplotype Association with Heroin Dependence in Chinese Population. [PDF]
PLoS ONE, 2015 Substance dependence is a frequently observed comorbid disorder in schizophrenia, but little is known about genetic factors possibly shared between the two psychotic disorders.
Yung Su Kim +14 more
doaj +3 more sources
Association between serotonin transporter gene polymorphisms and heroin dependence: a meta-analytic study [PDF]
Neuropsychiatric Disease and Treatment, 2016 Pao-Yen Lin,* Yi-Shan Wu* Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan *These authors contributed equally to this work Background: Studies have examined the ...
Lin PY, Wu YS
doaj +3 more sources
Association analysis of GABRB3 promoter variants with heroin dependence. [PDF]
PLoS ONE, 2014 GABRB3 encoding the β3 subunit of GABAA receptor has been implicated in multiple neuropsychiatric disorders, including substance abuse. Previous studies reported that SNPs at the 5' regulatory region of GABRB3 could regulate GABRB3 gene expression and ...
Chia-Hsiang Chen +2 more
doaj +3 more sources
Patterns and Predictors of Heroin Use, Remission, and Psychiatric Health Among People with Heroin Dependence: Key Findings from the 18-20-Year Follow-Up of the Australian Treatment Outcome Study (ATOS). [PDF]
Int J Ment Health Addict, 2023 This study aimed to investigate the long-term patterns and predictors of heroin use, dependence, and psychiatric health over 18–20 years among a cohort of Australians with heroin dependence, using a prospective longitudinal cohort study conducted in ...
Marel C +11 more
europepmc +2 more sources
Comorbidity of Mental Disorder in Patients with Chronic Disease: A Comparative Study of Heroin Dependence Patients and Diabetes Mellitus Patients [PDF]
Iranian Journal of Public Health, 2022 Background: Chronic patients are at greater risk for a psychiatric problem than the normal population; yet, the increased rate of mental disorder among one chronic patient compared to another chronic patient is uncertain.
Tahereh Seghatoleslam +3 more
doaj +2 more sources
Association studies of dopamine synthesis and metabolism genes with multiple phenotypes of heroin dependence [PDF]
BMC Medical Genetics, 2020 Background Heroin dependence is a complex disease with multiple phenotypes. Classification of heroin users into more homogeneous subgroups on the basis of these phenotypes could help to identify the involved genetic factors and precise treatments.
Yunxiao Li +6 more
doaj +2 more sources
Prevalence and correlates of suicide attempt among Chinese individuals receiving methadone maintenance treatment for heroin dependence. [PDF]
Sci Rep, 2019 To date, there have been very limited studies regarding the clinical epidemiology of attempted suicide in Chinese individuals with heroin-dependence. The objective of this study was to examine the prevalence and correlates of suicide attempt in Chinese ...
Zhong BL, Xie WX, Zhu JH, Lu J, Chen H.
europepmc +2 more sources