Results 31 to 40 of about 1,704,994 (242)

Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence. [PDF]

PLoS ONE, 2013
BACKGROUND: Heroin dependence is a debilitating psychiatric disorder with complex inheritance. Since the dopaminergic system has a key role in rewarding mechanism of the brain, which is directly or indirectly targeted by most drugs of abuse, we focus on ...
Andrea Vereczkei, Zsolt Demetrovics, Anna Szekely, Peter Sarkozy, Peter Antal, Agnes Szilagyi, Maria Sasvari-Szekely, Csaba Barta   +7 more
doaj   +1 more source

The Chinese version of obsessive compulsive drug use scale: validation in outpatient methadone maintenance treatment program

BMC Psychiatry, 2020
Background The Obsessive Compulsive Drug Use Scale (OCDUS) measures the overall craving level within a period from a multidimensional perspective. However, no studies have addressed the validity of the new OCDUS factor structure, presented in 2016, in ...
Hengfen Gong, Yingying Zhang, Qihuan Ren, Zhirong Zhou, Huijing Zhou, Xirong Sun, Chencheng Zhang, Valerie Voon, Min Zhao, Shunying Yu   +9 more
doaj   +1 more source

Cost-effectiveness of buprenorphine and naltrexone treatments for heroin dependence in Malaysia. [PDF]

PLoS ONE, 2012
To aid public health policymaking, we studied the cost-effectiveness of buprenorphine, naltrexone, and placebo interventions for heroin dependence in Malaysia.We estimated the cost-effectiveness ratios of three treatments for heroin dependence. We used a
Jennifer Prah Ruger, Marek Chawarski, Mahmud Mazlan, Nora Ng, Richard Schottenfeld   +4 more
doaj   +1 more source

Effectiveness and cost-effectiveness of unsupervised buprenorphine-naloxone for the treatment of heroin dependence in a randomized waitlist controlled trial.

Drug and Alcohol Dependence, 2017
BACKGROUND Access to opioid agonist treatment can be associated with extensive waiting periods with significant health and financial burdens. This study aimed to determine whether patients with heroin dependence dispensed buprenorphine-naloxone weekly ...
A. Dunlop, Amanda L Brown, C. Oldmeadow, A. Harris, Anthony Gill, Craig Sadler, K. Ribbons, J. Attia, D. Barker, P. Ghijben, J. Hinman, Melissa A. Jackson, J. Bell, N. Lintzeris   +13 more
semanticscholar   +1 more source

Evaluation of the Association of Htr2a Gene Rs6313 Polymorphism with Heroin Dependence in a Sample from Northwest Iran

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021
Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in
Fatemeh Mahmoudi, Leila Mehdizadeh fanid, Narges Zeinalzadeh, Mohammad ali Hosseinpour feizy   +3 more
doaj  

Reduction in cerebral perfusion after heroin administration: a resting state arterial spin labeling study. [PDF]

PLoS ONE, 2013
Heroin dependence is a chronic relapsing brain disorder, characterized by the compulsion to seek and use heroin. Heroin itself has a strong potential to produce subjective experiences characterized by intense euphoria, relaxation and release from craving.
Niklaus Denier, Hana Gerber, Marc Vogel, Markus Klarhöfer, Anita Riecher-Rossler, Gerhard A Wiesbeck, Undine E Lang, Stefan Borgwardt, Marc Walter   +8 more
doaj   +1 more source

Effects of Psychopathy on Neurocognitive Domains of Impulsivity in Abstinent Opiate and Stimulant Users

Frontiers in Psychiatry, 2021
Background: Psychopathy and substance use disorders (SUDs) are both characterized by neurocognitive impairments reflecting higher levels of impulsivity such as reward-driven decision-making and deficient inhibitory control.
Elena Psederska, Elena Psederska, Nicholas D. Thomson, Nicholas D. Thomson, Kiril Bozgunov, Dimitar Nedelchev, Georgi Vasilev, Jasmin Vassileva, Jasmin Vassileva   +8 more
doaj   +1 more source

Caregiver burden on wives of substance-dependent husbands and its correlates at a Tertiary Care Centre in Northern India

Indian Journal of Public Health, 2017
Background: Substance dependence is well recognized as a complex biopsychosocial phenomenon. Complications arising out of it not only impairs life of substance-dependent patient but also causes enormous burden on their caregivers.
Bharat Singh Shekhawat, Shreyance Jain, Hariom Kumar Solanki   +2 more
doaj   +1 more source

Assessment of sexual behavior among patients seeking treatment for opioid dependence and their knowledge and attitude about high-risk sexual behavior: A cross-sectional observational study

Indian Journal of Social Psychiatry, 2020
Aims: The primary aim of the current study was to assess the sexual history and behavior among treatment-naïve male patients of heroin dependence presenting to outpatient services; their knowledge and attitude about high-risk sexual behavior; and their ...
Nishtha Chawla, Suraj Verma, Siddharth Sarkar, Atul Ambekar   +3 more
doaj   +1 more source

Neurocognitive and Psychiatric Markers for Addiction: Common vs. Specific Endophenotypes for Heroin and Amphetamine Dependence

Current Topics in Medicinal Chemistry, 2020
Background: The differential utility of neurocognitive impulsivity and externalizing/internalizing traits as putative endophenotypes for dependence on heroin vs. amphetamine is unclear.
Elizabeth C. Long, R. Kaneva, G. Vasilev, F. G. Moeller, Jasmin Vassileva   +4 more
semanticscholar   +1 more source