Genetic analysis of AUTS2 as a susceptibility gene of heroin dependence [PDF]
, 2012 [[abstract]]BACKGROUND:Both alcoholism and heroin dependence are common substance use disorders with a high genetic basis. A recent genetic study reported that the autism susceptibility candidate 2 gene (AUTS2) was involved in regulating the alcohol ...
Chen, YH;Liao, DL;Lai, CH;Chen, CH
core +1 more source
Psychiatric comorbidity in young heroin users [PDF]
, 2006 In order to determine the prevalence of psychiatric comorbidity in a population of young heroin users recruited from outside of the healthcare context, a sample was assembled by targeted sampling and nomination techniques; it was comprised of regular ...
Rodriguez-Llera, MC, +5 more
core +1 more source
Heroin Dependence Duration Influences the Metabolic Parameters Mechanisms and Consequences of Impaired Insulin Sensitivity in Hepatitis C Virus Seronegative Heroin Dependents [PDF]
, 2012 Objective: Carbohydrate metabolism disorder in heroin dependence is an issue with long history and contradicting results. The aim of the study was to evaluate basal insulin sensitivity in hepatitis C virus seronegative heroin dependents with normal body ...
Cakalarovski, Koco +16 more
core +1 more source
Cost-effectiveness of buprenorphine and naltrexone treatments for heroin dependence in Malaysia. [PDF]
PLoS ONE, 2012 To aid public health policymaking, we studied the cost-effectiveness of buprenorphine, naltrexone, and placebo interventions for heroin dependence in Malaysia.We estimated the cost-effectiveness ratios of three treatments for heroin dependence. We used a
Jennifer Prah Ruger +4 more
doaj +1 more source
Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]
, 1998 The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Krappel, C. +9 more
core +1 more source
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021 Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in
Fatemeh Mahmoudi +3 more
doaj
BMC Psychiatry, 2020 Background The Obsessive Compulsive Drug Use Scale (OCDUS) measures the overall craving level within a period from a multidimensional perspective. However, no studies have addressed the validity of the new OCDUS factor structure, presented in 2016, in ...
Hengfen Gong +9 more
doaj +1 more source
Methadone treatment for opiate dependent patients in general practice and specialist clinic settings : outcomes at one-year follow-up [PDF]
, 2004 Few studies have investigated methadone maintenance treatment of opiate dependent patients in primary health care settings compared to specialist clinic settings.
Petitjean Gottfried, Sylvie
core +1 more source
Reduction in cerebral perfusion after heroin administration: a resting state arterial spin labeling study. [PDF]
PLoS ONE, 2013 Heroin dependence is a chronic relapsing brain disorder, characterized by the compulsion to seek and use heroin. Heroin itself has a strong potential to produce subjective experiences characterized by intense euphoria, relaxation and release from craving.
Niklaus Denier +8 more
doaj +1 more source
Frontiers in Psychiatry, 2021 Background: Psychopathy and substance use disorders (SUDs) are both characterized by neurocognitive impairments reflecting higher levels of impulsivity such as reward-driven decision-making and deficient inhibitory control.
Elena Psederska +8 more
doaj +1 more source