GRK5 Is Associated with the Regulation of Methadone Dosage in Heroin Dependence. [PDF]
Int J Neuropsychopharmacol, 2018 Background There is no countable biomarker for opioid dependence treatment responses thus far. In this study, we recruited Taiwanese methadone maintenance treatment patients to search for genes involving the regulatory mechanisms of methadone dose by ...
Wang SC +9 more
europepmc +2 more sources
Neural Correlates of Drug-Related Attentional Bias in Heroin Dependence. [PDF]
Front Hum Neurosci, 2017 The attention of drug-dependent persons tends to be captured by stimuli associated with drug consumption. This involuntary cognitive process is considered as attentional bias (AB).
Zhao Q +6 more
europepmc +2 more sources
Australian treatment outcome study: protocol for the 18–20-year follow-up of a prospective longitudinal cohort examining the natural history of heroin dependence and associated mortality, psychiatric and physical health, and health service use [PDF]
BMJ Open, 2020 Introduction Opioid dependence is a global health priority, currently making the biggest contribution to drug-related deaths. The chronic, long-term persistence of heroin dependence over the life course requires investigation in prospective longitudinal ...
Maree Teesson +11 more
doaj +2 more sources
Co-occurring Attention Deficit Hyperactivity Disorder symptoms in adults affected by heroin dependence: Patients characteristics and treatment needs. [PDF]
Psychiatry Res, 2017 Attention Deficit Hyperactivity Disorder (ADHD) is a risk for substance use disorders. The aim of this study was to investigate the association between adult ADHD symptoms, opioid use disorder, life dysfunction and co-occurring psychiatric symptoms. 1057
Lugoboni F +7 more
europepmc +2 more sources
Exendin-4 enhances GLP-1 signaling and reduces anxiety-like behaviors in male heroin withdrawal mice. [PDF]
PLoS ONEAnxiety and depression significantly contribute to heroin relapse, and addressing these issues could lower relapse rates. The basolateral amygdala (BLA) and nucleus tractus solitarius (NTS) are involved in regulating these emotions, but the molecular ...
Yang Xiang +9 more
doaj +2 more sources
The Professional Medical Journal, 2014 Objective: To determine the frequency and level of family support in Heroin Dependent patients presenting with 1st treatment and also the patients presenting with relapses. Study design: A descriptive study.
N. Maqsood +3 more
semanticscholar +3 more sources
Chronic Heroin Dependence Leading to Adrenal Insufficiency [PDF]
Case Reports in Endocrinology, 2014 Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on
Gautam Das
doaj +2 more sources
Opioid Receptors Gene Polymorphism and Heroin Dependence in Iran [PDF]
Basic and Clinical Neuroscience, 2018 Introduction: Genes often have multiple polymorphisms that interact with each other and the environment in different individuals. Variability in the opioid receptors can influence opiate withdrawal and dependence.
Sara Soleimani Asl +7 more
doaj +2 more sources
Drug and Alcohol Dependence, 2018 Background and Aims: Little is known about transition pathways among heroin users prior to treatment. This study examined the demographic and clinical predictors of transition speed from heroin use, to dependence, to first treatment episode.
Briony Larance +2 more
exaly +2 more sources
Effect of PDYN rs2281285, rs2235749 and rs910080 gene polymorphisms on the intensity of depression symptoms and negative craving in heroin addicts [PDF]
Archives of Biological Sciences, 2021 The present study was undertaken to explore whether prodynorphin (PDYN) polymorphisms have an effect on the intensity of depressive symptoms and negative craving in heroin addicts in a sample of 100 heroin addicts and 108 controls.
Kaya-Akyüzlü Dilek +3 more
doaj +1 more source