Results 41 to 50 of about 1,704,994 (242)

Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment

Neuropsychopharmacology Reports, 2023
Aim Although studies in Western countries have investigated the quality of life (QoL) of heroin users, limited research on this topic has been conducted in Asia.
Hu‐Ming Chang, Ming‐Chyi Huang, Su‐Chen Fang, Shih‐Ku Lin   +3 more
doaj   +1 more source

Allelic and genotypic associations of DRD2 TaqI A polymorphism with heroin dependence in Spanish subjects: a case control study

Behavioral and Brain Functions, 2007
Background Conflicting associations with heroin dependence have been found involving the A1 allele of dopamine D2 receptor gene (DRD2) TaqI A polymorphism.
Calafell Francesc, Banuls Enrique, Volpini Victor, Sinol Nuria, Trujols Joan, Baiget Montserrat, Perez de los Cobos Jose, Luquero Elena, del Rio Elisabeth, Alvarez Enric   +9 more
doaj   +1 more source

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

Drug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão, T. Rosado, M. Barroso, M. Andraus, E. Gallardo   +4 more
wiley   +1 more source

Decreased Relative Cerebral Blood Flow in Unmedicated Heroin-Dependent Individuals

Frontiers in Psychiatry, 2020
Understanding the brain mechanisms of heroin dependence is invaluable for developing effective treatment. Measurement of regional cerebral blood flow (CBF) provides a method to visualize brain circuits that are functionally impaired by heroin dependence.
Wenhan Yang, Ru Yang, Fei Tang, Jing Luo, Jun Zhang, Changlong Chen, Changlong Chen, Chunmei Duan, Yuan Deng, Lidan Fan, Jun Liu   +10 more
doaj   +1 more source

Assessment of Abuse Potential‐Related Effects of Oral Dried Kratom Leaf Powder in Healthy Normal Participants Following Single and Multiple Daily Doses

Drug Testing and Analysis, EarlyView.
In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe, Marilyn Huestis, Daniel Wang, Thomas Hudzik, John Bothmer, Jack Henningfield   +5 more
wiley   +1 more source

Do Injury, Depression, and PTSD Mediate the Relationships Between Latent Profiles of Cumulative Lifetime Violence and Chronic Pain Disability in Men?

Research in Nursing &Health, EarlyView.
ABSTRACT Knowledge of association between violence and chronic pain in men is limited by neglect of violence experiences as perpetrator, disregard of heterogeneity in cumulative lifetime violence severity (CLVS), weak understanding of mediation pathways, and inattention to social determinants of health (SDOH).
Judith Wuest, Sue O'Donnell, Kelly Scott‐Storey, Charlene D. Vincent, Jeannie Malcolm   +4 more
wiley   +1 more source

Assessing cue-induced brain response as a function of abstinence duration in heroin-dependent individuals: an event-related fMRI study. [PDF]

PLoS ONE, 2013
The brain activity induced by heroin-related cues may play a role in the maintenance of heroin dependence. Whether the reinforcement or processing biases construct an everlasting feature of heroin addiction remains to be resolved.
Qiang Li, Yarong Wang, Yi Zhang, Wei Li, Jia Zhu, Ying Zheng, Jiajie Chen, Liyan Zhao, Zhenyu Zhou, Yijun Liu, Wei Wang, Jie Tian   +11 more
doaj   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Rate and Predictors of Severe Withdrawal Symptoms in an Accelerated Opioid Detoxification Program

Psychiatry and Clinical Psychopharmacology, 2021
Background: Opioid addicts usually quit treatment due to the severe withdrawal symptoms associated with it. Accelerated opioid detoxification programs were launched with the aim of making the detoxification process easier to complete for opioid patients
Ozge Kalkan, Kultegin Ogel, Gizem Pozam, Hakan Sari   +3 more
doaj   +1 more source

Methadone Treatment for Heroin Dependence

Drug Addiction, 2018
In substitution therapy for treatment of heroin addiction, methadone is the synthetic opi- oid agonist of first choice. Methadone doses vary depending on addict profile established by repeated evaluation.
Baconi Daniela Luiza, A. Ciobanu, R. Vasile, A. Vlăsceanu, Mirela Nedelescu, M. Stan   +5 more
semanticscholar   +1 more source