Results 21 to 30 of about 1,016,909 (195)
Brain Sciences, 2012 Opiate withdrawal is followed by a protracted abstinence syndrome consisting of craving and physiological changes. However, few studies have been dedicated to both the characterization and understanding of these long-term alterations in post-dependent ...
Luis Stinus +2 more
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Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence. [PDF]
PLoS ONE, 2013 BACKGROUND: Heroin dependence is a debilitating psychiatric disorder with complex inheritance. Since the dopaminergic system has a key role in rewarding mechanism of the brain, which is directly or indirectly targeted by most drugs of abuse, we focus on ...
Andrea Vereczkei +7 more
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BMC Psychiatry, 2020 Background The Obsessive Compulsive Drug Use Scale (OCDUS) measures the overall craving level within a period from a multidimensional perspective. However, no studies have addressed the validity of the new OCDUS factor structure, presented in 2016, in ...
Hengfen Gong +9 more
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Cost-effectiveness of buprenorphine and naltrexone treatments for heroin dependence in Malaysia. [PDF]
PLoS ONE, 2012 To aid public health policymaking, we studied the cost-effectiveness of buprenorphine, naltrexone, and placebo interventions for heroin dependence in Malaysia.We estimated the cost-effectiveness ratios of three treatments for heroin dependence. We used a
Jennifer Prah Ruger +4 more
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Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021 Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in
Fatemeh Mahmoudi +3 more
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Reduction in cerebral perfusion after heroin administration: a resting state arterial spin labeling study. [PDF]
PLoS ONE, 2013 Heroin dependence is a chronic relapsing brain disorder, characterized by the compulsion to seek and use heroin. Heroin itself has a strong potential to produce subjective experiences characterized by intense euphoria, relaxation and release from craving.
Niklaus Denier +8 more
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Frontiers in Psychiatry, 2021 Background: Psychopathy and substance use disorders (SUDs) are both characterized by neurocognitive impairments reflecting higher levels of impulsivity such as reward-driven decision-making and deficient inhibitory control.
Elena Psederska +8 more
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EEG spectral power and mean frequencies in early heroin abstinence
, 2004 The purpose of the present study was to investigate cumulative heroin effects on brain functioning by studying relationships between EEG spectral power and mean frequencies and heroin abusing history.
Davydov, Dmitry M., Polunina, Anna G.
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Direct, indirect and epistatic associations of reward system genes with heroin dependence
, 2021 Objective: Genes encoding molecular pathways of the reward system are implicated in both addiction and impulsivity. A complex interplay of these genes is likely to contribute to the risk and perpetuation of addiction, both directly and indirectly ...
Daglish, M +6 more
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Indian Journal of Public Health, 2017 Background: Substance dependence is well recognized as a complex biopsychosocial phenomenon. Complications arising out of it not only impairs life of substance-dependent patient but also causes enormous burden on their caregivers.
Bharat Singh Shekhawat +2 more
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