Results 51 to 60 of about 24,412 (283)

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

open access: yesDrug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza   +7 more
wiley   +1 more source

Assessing cue-induced brain response as a function of abstinence duration in heroin-dependent individuals: an event-related fMRI study. [PDF]

open access: yesPLoS ONE, 2013
The brain activity induced by heroin-related cues may play a role in the maintenance of heroin dependence. Whether the reinforcement or processing biases construct an everlasting feature of heroin addiction remains to be resolved.
Qiang Li   +11 more
doaj   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

The role of concomitant drugs in the aetiology of fatal heroin- and methadone- related overdose [PDF]

open access: yes, 2008
Heroin and methadone poisoning are significant causes of death of young people in the United Kingdom. In a high proportion of these fatalities concomitant substances are also detected.
Oliver, Phillip
core  

Rate and Predictors of Severe Withdrawal Symptoms in an Accelerated Opioid Detoxification Program

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Background: Opioid addicts usually quit treatment due to the severe withdrawal symptoms associated with it. Accelerated opioid detoxification programs were launched with the aim of making the detoxification process easier to complete for opioid patients
Ozge Kalkan   +3 more
doaj   +1 more source

Nanoelectronic Detection of Opioids: Machine Learning‐Powered Screening With Carbon Nanotube Field‐Effect Transistor Sensor Array

open access: yesSmall, EarlyView.
A carbon nanotube field‐effect transistor (NTFET) sensor array is constructed to screen different opioids with machine learning models. Codeine, fentanyl, hydrocodone, and morphine are tested using the NTFET sensor array and classified with both conventional supervised learning models and deep learning models.
Zhengru Liu   +7 more
wiley   +1 more source

Clinical and psychosocial predictors of attendance and drug use in heroin users undergoing treatment [PDF]

open access: yes, 2008
The main aim of this thesis is to evaluate the Theory of Planned Behaviour's ability to identify predictors of intention and behaviour. The population of interest are heroin users; the behaviours are attendance at treatment services and heroin use during
Horspool, Michelle J   +1 more
core  

Enlarged cerebrospinal fluid spaces in opiate-dependent male patients: A stereological CT study [PDF]

open access: yes, 1998
Computed tomography was performed in 9 male patients with a diagnosis of opiate dependence and in 9 age-matched psychiatric controls (neurotic depression).
Van Roost, Dirk   +9 more
core   +1 more source

Differences in onset and abuse/dependence episodes between prescription opioids and heroin: results from the National Epidemiologic Survey on Alcohol and Related Conditions

open access: yesSubstance Abuse and Rehabilitation, 2011
Li-Tzy Wu1, George E Woody2, Chongming Yang3, Paolo Mannelli1, Dan G Blazer11Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, NC, USA; 2Department of Psychiatry, University of ...
Mannelli P   +4 more
doaj  

Medical diagnoses associated with substance dependence among inpatients at a large urban hospital.

open access: yesPLoS ONE, 2015
BackgroundThere are limited data on reasons for hospital admission among patients dependent on substances other than alcohol. We compared primary discharge diagnoses for heroin- or cocaine-dependent patients to non-dependent patients.Material and ...
Humberto Choi   +3 more
doaj   +1 more source

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