Alcohol consumption in Colombian university students
Introduction: Alcohol consumption is conceived as a public health problem. Given the significant prevalence of consumption and its negative consequences, it is necessary to contribute to the prevention from the identification of populations at risk, such
Sonia Betancourth Zambrano +2 more
doaj +1 more source
Community acceptance and implementation of HIV prevention interventions for injection drug users [PDF]
In 1997, the National Institutes of Health (NIH) reviewed evidence of the effectiveness of HIV prevention programs for injection drug users (IDUs) and recommended that three types ofinterventions be implemented to prevent transmission of HIV among IDUs ...
Brian R. Edlin +6 more
core
Prevalence of drug-herb and drug-supplement interactions in older adults : A cross-sectional survey [PDF]
© British Journal of General PracticeBackground Polypharmacy is common among older adults, with increasing numbers also using prescription drugs with herbal medicinal products (HMPs) and dietary supplements.
Agbabiaka +19 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
THE CORRELATION BETWEEN POOR ORAL HYGIENE AND ORAL HEALTH-RELATED QUALITY OF LIFE AMONG DRUG USERS
Background: The quality of life among drug users has become an increasingly important public health issue. One of the factors suspected to contribute to this is poor oral hygiene, which may result from reduced saliva production due to long-term use of ...
Riky Hamdani +2 more
doaj +1 more source
Supervised Injection Facilities: Legal and Policy Reforms [PDF]
The US Centers for Disease Control and Prevention reported that more than 70 000 deaths from drug overdoses occurred in 2017, including prescription and illicit opioids, representing a 6-fold increase since 1999.
Gostin, Lawrence O. +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Beyond Addiction: Burden of Polypharmacy and Risk in Frail Patients with Substance Use Disorder
Substance use disorder (SUD) is a chronic and clinically complex condition, frequently complicated by significant organic and psychiatric comorbidities. Most patients are polymedicated and require opioid substitution programs (OSPs).
L. Goretti Santiago Gutiérrez +8 more
doaj +1 more source
Breathlessness in a drug user [PDF]
A 40-year-old heroin smoking man presented with acute onset severe shortness of breath. Radiological investigations revealed an unexpected loculated pneumothorax. Respiratory physicians inserted a chest drain which relieved his breathlessness. His exercise tolerance is much improved 6 months on. The side effects of smoking illicit substances are poorly
openaire +2 more sources
Why Do Some People Want to Legalize Cannabis Use? [PDF]
Preferences and attitudes to illicit drug policy held by individuals are likely to be an important in uence in the development of illicit drug policy.
Grossmann, M. +2 more
core +1 more source

