Results 121 to 130 of about 839,545 (360)

Market Analysis of Synthetic Drugs: Amphetamine-type Stimulants, New Psychoactive Substances [PDF]

, 2017
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...

core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Acute Suppurative Thyroiditis in an Intravenous Drug User with a Preexisting Goiter [PDF]

, 2018
Nikhil Yegya‐Raman, Tabitha Copeland, Payal Parikh   +2 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

From Education to Action—The Impact of Hepatitis C Micro‐Elimination Education on Healthcare Provider Confidence and Linkage to Care: A Quasi‐Experimental Study

Health Science Reports
Background and Aim Micro‐elimination education can improve access to life‐saving treatments for patients with hepatitis C, co‐occurring mental health conditions, and alcohol and other drug use disorders.
Regan Preston, Eric Lim, Shirley McGough, Glenn Boardman, Karen Heslop   +4 more
doaj   +1 more source

Does the sedation regimen affect adverse events during procedural sedation and analgesia in injection drug users? [PDF]

, 2013
Frank Scheuermeyer, Gary Andolfatto, Hong Qian, Eric Grafstein   +3 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

HIV IN ILLICIT DRUG USERS

Clinics in Chest Medicine, 1996
Illicit drug users comprise a substantial and growing proportion of the HIV-infected population. Although they develop pulmonary complications common to all HIV transmission groups, they also have unique respiratory illnesses due to the direct effect of the illicit drugs on the lung.
openaire   +2 more sources

Policy for Drug Users in Indonesia: A Critical Policy Analysis of Jail Punishment and an Alternate Rehabilitation Policy [PDF]

, 2014
I Nyoman Sutarsa
openalex   +1 more source