Results 131 to 140 of about 841,619 (362)
Health Science ReportsBackground and Aim Micro‐elimination education can improve access to life‐saving treatments for patients with hepatitis C, co‐occurring mental health conditions, and alcohol and other drug use disorders.
Regan Preston +4 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Hazardous Drinkers and Drug Users in HMO Primary Care: Prevalence, Medical Conditions and Costs [PDF]
, 2006 Summarizes a study of the links between frequent heavy drinking and drug use and medical conditions, the frequency of hazardous drinkers' and drug users' primary care and psychiatry visits, and the resulting costs of their health ...
Deanna Lewis, Jennifer Mertens
core
Correction: Are Current Drug Driving Enforcement Strategies Achieving the Desired Effect? Drug Users’ Perceptions of Drug Driving Legislation and Enforcement in Queensland [PDF]
Steven Love +3 more
openalex +1 more source