Results 121 to 130 of about 841,619 (362)
Comparison of the Effectiveness of Cognitive Bias Correction in Real and Placebo Modes
Armaghane Danesh Bimonthly Journal, 2019 Background & aim: Inability to control drug use is one of the main aspects of drug dependence. Part of this disability is due to the cognitive biases that result from people's constant exposure to substances.
F Zeraat Herfeh +2 more
doaj
Demographic, Risk, and Spatial Factors Associated With Over-the-Counter Syringe Purchase Among Injection Drug Users [PDF]
, 2012 Thomas J. Stopka +5 more
openalex +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Concept of harm reduction: part 1
Journal of Health Science and Medical Research (JHSMR), 2007 A Thai government policy taking measures to curb the use of illicit drugs has changed the pattern of use away from heroin to other alternatives such as dormicum (Midazolam), hypnotics, and alcohol, which are not suitable for intravenous injection ...
N Apakupakul
doaj
Drug Use and Capital Accumulation [PDF]
This paper admits that people are drug users and analyzes whether drug use affects the modified golden rule in the Ramsey model approach. The results show that in a steady state, this model's capital productivity is smaller than in the Ramsey model ...
Adolfo Sachsida +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Clinics in Chest Medicine, 1996 Illicit drug users comprise a substantial and growing proportion of the HIV-infected population. Although they develop pulmonary complications common to all HIV transmission groups, they also have unique respiratory illnesses due to the direct effect of the illicit drugs on the lung.
openaire +2 more sources
Differences in the social networks of ethnic Vietnamese and non-Vietnamese injecting drug users and their implications for blood-borne virus transmission [PDF]
, 2007 Campbell Aitken, Peter Higgs, S. Bowden
openalex +1 more source
GDNF‐RET signaling drives pulmonary neuroendocrine cell hyperplasia and allergic airway inflammation
FEBS Letters, EarlyView.A neuroimmune interaction centered on the PNEC‐ILC2 axis in an asthma model. PNEC‐derived CGRP activates nearby ILC2s, which then release cytokines, including IL‐5 and IL‐13. These cytokines promote eosinophil and macrophage infiltration. Subsequently, GDNF produced by these cells induces PNEC hyperplasia via the GDNF receptors, RET and GFRα1 ...
Tasuku Kawano +3 more
wiley +1 more source