Results 181 to 190 of about 839,545 (360)

No evidence of compensatory drug use risk behavior among heroin users after receiving take-home naloxone

, 2017
Jermaine D. Jones, Aimee Campbell, Verena E. Metz, Sandra D. Comer   +3 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Willingness to use fentanyl test strips among street drug users in Puerto Rico: a cross-sectional study. [PDF]

Harm Reduct J
Reyes Orlando L, Colón Jordán HM, Rosario Santos AM.   +2 more
europepmc   +1 more source

Features of the Clinical Course of Odontogenic Inflammatory Diseases of the Jaws and Soft Tissues in Drug Users

Оleksii Tymofieiev, Оlena Vesova, Natalia Ushko, Sergii Maksymcha, Anna Kryvosheieva   +4 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Assessment of Bacterial Infections and Antibiotic Regimens in Intravenous Drug Users. [PDF]

Cureus, 2023
Rehman S, Arif S, Ushakumari LG, Amreen J, Nagelli A, Moonnumackel SJ, Nair A.   +6 more
europepmc   +1 more source

Drugs and Growth-Efficient Prevention: An Inter-temporal Portfolio of Machos, Narcos and Angels [PDF]

In many countries substance abuse is a social epidemic. This paper deals conceptually with some macroeconomic aspects of widespread substance abuse with special reference to narcotic drugs.
Levy, Amnon, Neri, Frank
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The impact of institutionalization on the effectiveness of harm reduction: a qualitative study using drug users' representations. [PDF]

Harm Reduct J
Khatmi N, Dany L, Roux P.
europepmc   +1 more source

Intravenous Drug User [PDF]

, 2020
openaire   +1 more source