Results 161 to 170 of about 841,619 (362)
Policy for Drug Users in Indonesia: A Critical Policy Analysis of Jail Punishment and an Alternate Rehabilitation Policy [PDF]
, 2014 I Nyoman Sutarsa
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Comparing Quality of Life Among Female Sex Workers With and Without Addiction
Journal of Client-centered Nursing Care, 2016 Background: Prostitution and substance abuse are among the crucial social problems in women, which affect the quality of life. However, no study has yet investigated that prostitution and substance abuse affect which dimension(s) of quality of life.
Anahita Khodabakhshi Koolaee +1 more
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Self-efficacy and Self-esteem in Wives With Addicted Husbands
Journal of Holistic Nursing and Midwifery, 2019 Introduction: Husband’s addiction often leads to the disruption of family roles and duties. In this process, women as wives in families with addicted husbands may tolerate pressures from everywhere and are emotionally, physically, mentally, and ...
Mahsa Shaali +3 more
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Alternative beliefs in psychedelic drug users. [PDF]
Sci Rep, 2023 Lebedev AV +7 more
europepmc +1 more source
OSC13: Temporomandibular disorders among drug users in Indonesia
, 2018 Inge Paramitha +2 more
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