Results 171 to 180 of about 841,619 (362)

Users of antiasthma drugs in Iceland: a drug utilization study [PDF]

, 1997
T. Gislason, O Olafsson, A Sigvaldason
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Development and validation of a risk prediction model for small intestinal mucosal injury in nonsteroidal anti-inflammatory drug users. [PDF]

World J Gastrointest Surg
Zhao NH, Zhao LR, Yao J, Niu LY, Yang LJ, Lin YJ, Liu M.   +6 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Oral Health Disparities among Illicit Drug Users in the US: Secondary Analysis using Data from NHANES 2017-2018. [PDF]

Oral Health Prev Dent
Farsi N, Ashi H, Alwafi A, Abuljadayel L, Samman M, Bamashmous M, Meisha D, Sabbahi D.   +7 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Impact of intraoperative methadone on early extubation and opioid utilization in intravenous drug users undergoing cardiac surgery. [PDF]

BMC Anesthesiol
Hoff A, Ellison MB, Kabulski G, Statler A, Funke CD, Hayanga JWA, Ellison PR.   +6 more
europepmc   +1 more source

The Correlation between Alcohol Consumption with Anxiety Level on Multiple Drugs User in Sleman

, 2020
Andrian Fajar Kusumadewi, Carissa Aulia Firliany, Silas Henry Ismanto, Afkar Aulia   +3 more
openalex   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Distribution patterns of narcotic drugs, psychotropic substances, and new psychoactive substances among reported drug users in china (2014-2026): A systematic review and Meta-Analysis. [PDF]

Addict Behav Rep
Wang Q, Qin Z, Qin L, Xing X, Wang Z, Cui H, Zhang J, Xing Y, Chen J, Zhao M, Luo W, Zhu H, Jia Z.   +12 more
europepmc   +1 more source