Results 211 to 220 of about 841,619 (362)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne +61 morewiley +1 more sourceYeast fungaemia among injection drug users in France (2012-2022): a cross-sectional observational study. [PDF]
Lancet Reg Health EurPaccoud O, Lortholary O, Imbert S, Letscher-Bru V, Boukris-Sitbon K, Obadia T, Dalle F, Hasseine L, Morio F, Huguenin A, Poirier P, Favennec L, Bonhomme J, Alanio A, Lanternier F, Desnos-Ollivier M, French Mycoses Study Group. +16 moreeuropepmc +1 more sourceIMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd +9 morewiley +1 more sourceSingle and multiple switches, swap and retransitioning among 28,073 biological drug users with inflammatory bowel diseases: results from the Italian VALORE network. [PDF]
Ther Adv GastroenterolPellegrini G, Spini A, Bellitto C, L'Abbate L, Ingrasciotta Y, Soardo F, Leoni O, Mazzone A, Ancona D, Stella P, Cavazzana A, Scapin A, Lopes S, Belleudi V, Ledda S, Carta P, Rossi P, Ejlli L, Sapigni E, Puccini A, Scarpelli RF, De Sarro G, Tuccori M, Gini R, Allotta A, Addario Pollina S, Da Cas R, Bucaneve G, Mangano AMP, Balducci F, Sorrentino C, Senesi I, Bernardi FF, Trama U, Spila Alegiani S, Mayer F, Massari M, Savarino EV, Variola A, Trifirò G. +39 moreeuropepmc +1 more sourceIncidence of hepatitis C virus infection among injection drug users during an outbreak of HIV infection.
, 2001 David M. Patrick, Mark Tyndall, Peter Cornelisse, Kathy Li, C.H. Sherlock, Michael L. Rekart, Steffanie A. Strathdee, Sue Currie, Martin T. Schechter, Michael V. O’Shaughnessy +9 moreopenalex Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer +13 morewiley +1 more sourceBurden, Risk Factors, and Knowledge of Non-fatal Opioid Overdose Among Injectable Drug Users: A Cross-sectional Study. [PDF]
Indian J Psychol MedDas S, Sen S, Mondal S, Mondal M, Khatun Y, Sarkhel S, Saha I, Mukherjee S, Bhowmik K, Sarkar S, Neogi R, Rao R, Paramanik M, Bhattacharjee M, Basu A, Bhargava S, Ganguly S, Bhattacharjee S, Saha A, Chakrabarti A. +19 moreeuropepmc +1 more source
