Advanced Intelligent Discovery, EarlyView.This article establishes a Taguchi–Bayesian sampling strategy to reconstruct polymer processing–property landscape at minimal sampling cost, generically building the roadmap for materials database construction from sampling their vast design space. This sampling strategy is featured by an alternating lesson between uniformity and representativeness ...
Han Liu, Liantang Li
wiley +1 more source
Modification patents across multiple NDAs in pharmaceutical protections. [PDF]
Health Aff SchFeldman R, Alsaffar R, Sakib T.
europepmc +1 more source
Evolution of Physical Intelligence Across Scales
Advanced Intelligent Discovery, EarlyView.By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu +7 more
wiley +1 more source
Pharmaceutical quality and cost-effectiveness of branded versus generic medicines across 22 drug types and 8 therapeutic categories: a citizen-funded comparative study from regulated retail outlets in Kerala, India. [PDF]
Front PharmacolPhilips CA +7 more
europepmc +1 more source
Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents
Advanced Intelligent Discovery, EarlyView.This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer +3 more
wiley +1 more source
COMPREHENSIVE TREATMENT OF PAIN-PARESTETICHESKOY GPRS USING PHYSIOTHERAPY
, 2018 Despite the significant prevalence in the population of major dental diseases is 30-70%, a relatively high proportion are pathological processes of periodontal tissues and mucous membranes of the mouth (GPRS). They hit 10-50% of the population.
Y.N. Dychko +3 more
core
Accelerating Subcutaneous Drug Development: A Mechanistic Absorption Model for the Open Systems Pharmacology Framework. [PDF]
CPT Pharmacometrics Syst PharmacolPellowe M, Dubbelboer I, Sjögren E.
europepmc +1 more source
A Unifying Approach to Self‐Organizing Systems Interacting via Conservation Laws
Advanced Intelligent Discovery, EarlyView.The article develops a unified way to model and analyze self‐organizing systems whose interactions are constrained by conservation laws. It represents physical/biological/engineered networks as graphs and builds projection operators (from incidence/cycle structure) that enforce those constraints and decompose network variables into constrained versus ...
F. Barrows +7 more
wiley +1 more source
PERSEPSI FARMASIS TENTANG KEBIJAKAN SUBSTITUSI GENERIK DAN PELAKSANAANNYA DI KABUPATEN KONAWE
, 2011 Background: Medicine is one of an irreplaceable component of health care because medicine is the main intervention to improve health. Medication is also often become the most expensive component of health. The result of drug survey research by Budiharto (
, dr. Rustamaji, M.Kes. +1 more
core
Evaluation of the Utilization Pattern of Veterinary Drugs in Selected Veterinary Clinics of Mekelle City, Tigray, Ethiopia. [PDF]
Vet Med SciHagos H +3 more
europepmc +1 more source