Advanced Intelligent Discovery, EarlyView.This article establishes a Taguchi–Bayesian sampling strategy to reconstruct polymer processing–property landscape at minimal sampling cost, generically building the roadmap for materials database construction from sampling their vast design space. This sampling strategy is featured by an alternating lesson between uniformity and representativeness ...
Han Liu, Liantang Li
wiley +1 more source
Do publicly supported generic pharmacies improve financial risk protection? Findings from a nationally representative cross-sectional survey in India. [PDF]
BMJ OpenPurohit N +12 more
europepmc +1 more source
Reference Pricing of Pharmaceuticals for Medicare: Evidence from Germany, the Netherlands and New Zealand [PDF]
This paper describes three prototypical systems of therapeutic reference pricing (RP) for pharmaceuticals -- Germany, the Netherlands, and New Zealand -- and examines their effects on the availability of new drugs, reimbursement levels, manufacturer ...
Jonathan D. Ketcham, Patricia M. Danzon
core
Advanced Intelligent Discovery, EarlyView.Chat computational fluid dynamics (CFD) introduces an large language model (LLM)‐driven agent that automates OpenFOAM simulations end‐to‐end, attaining 82.1% execution success and 68.12% physical fidelity across 315 benchmarks—far surpassing prior systems.
E Fan +8 more
wiley +1 more source
<i>In vitro</i> Bioequivalence Analysis of Generic Metformin Hydrochloride Film-coated Tablets. [PDF]
Acta Med PhilippBuenavidez ZP +7 more
europepmc +1 more source
Evolution of Physical Intelligence Across Scales
Advanced Intelligent Discovery, EarlyView.By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu +7 more
wiley +1 more source
Parental preferences for generic substitution policies for children in China: a discrete choice experiment. [PDF]
BMJ OpenPu T +5 more
europepmc +1 more source
Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents
Advanced Intelligent Discovery, EarlyView.This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer +3 more
wiley +1 more source
Impact of a National Volume-Based Procurement Policy in China on purchase of nucleoside/nucleotide analog drugs for the treatment of chronic hepatitis B virus infection. [PDF]
BMC Public HealthYang Z +11 more
europepmc +1 more source
A Unifying Approach to Self‐Organizing Systems Interacting via Conservation Laws
Advanced Intelligent Discovery, EarlyView.The article develops a unified way to model and analyze self‐organizing systems whose interactions are constrained by conservation laws. It represents physical/biological/engineered networks as graphs and builds projection operators (from incidence/cycle structure) that enforce those constraints and decompose network variables into constrained versus ...
F. Barrows +7 more
wiley +1 more source