Results 41 to 50 of about 279,027 (307)
Medulloblastoma: Immune microenvironment and targeted nano-therapy
OpenNano, 2022 The tumor microenvironment (TME) plays key roles in tumor development, progressive and metastasis. Recently, therapy strategies based on TME targeted modulation shows potential to improve the efficacy of therapeutics, which attracted much attention in ...
Qiyue Wang, Ji Liu
doaj +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Butterfly wing scales are intricate cuticular functional nanosctructures. This perspective suggests that spatially varying material properties, cytoskeletal constraints, and growth‐driven mechanical instabilities shape the resulting nanoscale architectures created from single cells.
Anupama Prakash +10 more
wiley +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2023 This report summarizes the proceedings for day 2 sessions 1 and 3 of the 2‐day public workshop entitled “Regulatory Utility of Mechanistic Modeling to Support Alternative Bioequivalence Approaches,” a jointly sponsored workshop by the US Food and Drug ...
Fang Wu +17 more
doaj +1 more source
The Community Safety Net and Prescription Drug Access for Low-Income, Uninsured People [PDF]
, 2006 Examines strategies adopted by hospitals and community health centers to maintain access to affordable brand name and generic prescription drugs.
Anneliese M. Gerland +2 more
core
Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics
Advanced Functional Materials, EarlyView.Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha +15 more
wiley +1 more source
In Silico Methods for Development of Generic Drug–Device Combination Orally Inhaled Drug Products
CPT: Pharmacometrics & Systems Pharmacology, 2019 The development of generic, single‐entity, drug–device combination products for orally inhaled drug products is challenging in part because of the complex nature of device design characteristics and the difficulties associated with establishing ...
Ross L. Walenga +2 more
doaj +1 more source
Evaluation of model‐based bioequivalence approach for single sample pharmacokinetic studies
CPT: Pharmacometrics & Systems Pharmacology, 2023 In a traditional pharmacokinetic (PK) bioequivalence (BE) study, a two‐way crossover study is conducted, PK parameters (namely the area under the time‐concentration curve [AUC] and the maximal concentration [Cmax]) are obtained by noncompartmental ...
Coralie Tardivon +10 more
doaj +1 more source
Generic drugs: benefit/risk ratio
Неврология, нейропсихиатрия, психосоматика, 2021 The review discusses the interchangeability of medications, approaches to the registration of original and generic drugs, and types of their equivalence, as well as problems with generics in clinical practice.
E. A. Ushkalova +2 more
doaj +1 more source
Pricing of drugs and donations: options for sustainable equity pricing. [PDF]
, 2001 Effective medicines exist to treat or alleviate many diseases which predominate in the developing world and cause high mortality and morbidity rates. Price should not be an obstacle preventing access to these medicines.
Ford, N, Herranz, E, Pérez-Casas, C
core +2 more sources