Association of Medication Use and 8-Year Mortality Risk in Patients With Parkinson Disease: Drug-Wide Trial Emulation. [PDF]
Tuominen JA+7 more
europepmc +1 more source
Functional parameters of spermatozoa obtained by a new selection device
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez+8 more
wiley +1 more source
Streamlining one-dose package-handling process improves operational efficiency when dispensing drugs: A retrospective study. [PDF]
Kato T+4 more
europepmc +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis+3 more
wiley +1 more source
Cataloging Actionable Pharmacogenomic Variants for Indian Clinical Practice: A Scoping Review. [PDF]
Kulkarni SS, R V, Das A, Iyer GR.
europepmc +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang+6 more
wiley +1 more source
Characteristics of medical costs and resource use in patients with rheumatoid arthritis treated with and without glucocorticoids. [PDF]
Tanaka E+5 more
europepmc +1 more source
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash+6 more
wiley +1 more source
Peptide Drug: Design and Clinical Applications. [PDF]
Han Y, Zhang Y, Li H, Ma Z, Wang Y.
europepmc +1 more source
Liver‐specific lncRNAs associated with liver cancers
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina+3 more
wiley +1 more source