Results 51 to 60 of about 3,546,242 (318)
Drug–drug interaction analysis: Antituberculosis drugs versus antiretroviral drugs
Background: Human immunodeficiency virus (HIV) infection is an important public health globally. An important concomitant medical disorder among HIV-infected patients is tuberculosis. The management of concurrent infection between HIV and tuberculosis is usually difficult. The concomitant use of antituberculosis drug and antiretroviral drug is required.
Won Sriwijitalai, Viroj Wiwanitkit
openaire +2 more sources
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Recreational Use of Nitrous Oxide – a Growing Concern in Europe
Introduction: Nitrous oxide, commonly known as laughing gas, is used medically as an analgesic and anaesthetic. It has been used recreationally for its brief euphoric effects for over 200 years, however, in the last decade, there has been a large ...
J. De Morais +16 more
doaj +1 more source
A series of new trimethoxyphenyl-4H-chromen derivatives as telomerase inhibitors through regulation dyskerin were designed and synthesised. The anticancer activity assay in vitro showed that compound 5i 3-(4-(4-isonicotinoylpiperazin-1-yl)butoxy)-5,7 ...
Jie Quan Wang +6 more
doaj +1 more source
National post-market surveillance assessment of veterinary medicines in Korea during the past decade
Background Veterinary medicines have been widely used for the prevention and treatment of diseases, growth promotion, and to promote feeding efficacy in livestock. As the veterinary medicine industry has steadily grown, it is crucial to set up a baseline
JeongWoo Kang +9 more
doaj +1 more source
Sea urchins (Echinoidea) are key components of marine benthic communities and many are commercially important fishery resources as luxury and healthy seafood. However, despite their high ecological and economic value, the mitochondrial genomes of all sea
Shengping Zhong +4 more
doaj +1 more source
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source
Rosuvastatin calcium is a widely used 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitor developed for the treatment of dyslipidemia. To establish a control strategy for the elemental impurities, a new digestion method combined with an inductively
Yajie Hao +7 more
doaj +1 more source
689P DB-1305 (a Trop-2 targeted antibody-drug-conjugate [ADC]) in patients (pts) with advanced solid tumors: Preliminary clinical results from the phase (Ph) I/IIa study [PDF]
Omkar Marathe +19 more
openalex +1 more source
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher +8 more
wiley +1 more source

