The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]
, 2020 Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Bacinschi, Nicolae +6 more
core +2 more sources
Machine Learning Approach to Drug Treatment Strategy for Diabetes Care [PDF]
, 2023 Kazuya Fujihara, Hirohito Sone
openalex +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Silver-catalyzed remote Csp3-H functionalization of aliphatic alcohols
Nature Communications, 2018 Aliphatic alcohols usually require pre-activation for successful functionalization of their carbon chain. Here, the authors report a silver-catalyzed δ-selective functionalization of aliphatic alcohols via Csp3-H bond cleavage under mild conditions ...
Yuchao Zhu +9 more
doaj +1 more source
Mitochondrial DNA. Part B. Resources, 2021 Echinoderms (Echinodermata) are morphologically diverse and ecologically important groups of marine invertebrate, many of which are key components of local benthic ecosystem.
Shengping Zhong +4 more
doaj +1 more source
A survey of substance use for cognitive enhancement by university students in the Netherlands [PDF]
, 2015 Background: Pharmacological cognitive enhancement, using chemicals to change cellular processes in the brain in order to enhance one's cognitive capacities, is an often discussed phenomenon.
Bundt, Carsten +5 more
core +3 more sources
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Recent Advances in Chemistry and Bioactivities of Secondary Metabolites from the Genus Acremonium
Journal of FungiAcremonium fungi is one of the greatest and most complex genera in Hyphomycetes, comprising 130 species of marine and terrestrial sources. The past decades have witnessed substantial chemical and biological investigations on the diverse secondary ...
Yuning Qin +6 more
doaj +1 more source
Taking Drugs to Help Others [PDF]
, 2016 Every day the news shows us provoking stories about what's going on in the world, about events which raise moral questions and problems. In Philosophers Take On the World a team of philosophers get to grips with a variety of these controversial issues ...
Douglas, Thomas
core
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]
, 2016 The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani +11 more
core +3 more sources