Results 61 to 70 of about 15,961 (225)

Drusen classification and quantification in pseudophakic postmortem eyes implanted with or without blue-light filtering intraocular lenses

The Pan-American Journal of Ophthalmology
Purpose: To investigate the effect of blue-light filtering intraocular lenses on drusen formation in postmortem eyes via histopathological analysis.
Emmanuel Issa Bassam Nassrallah, Christina Mastromonaco, Emily Marcotte, Emma Youhnovska, Mohamed Abdouh, Miguel N. Burnier   +5 more
doaj   +1 more source

The prechoroidal cleft in neovascular age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 4, Page 364-375, June 2026.
Abstract The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–22% of neovascular age‐related macular degeneration (nAMD) eyes, most often with macular neovascularization
Niels J. Brouwer, T. H. Khanh Vu, Yvonne De Jong‐Hesse, Elon H. C. van Dijk   +3 more
wiley   +1 more source

Early Detection of Incipient Retinal Pigment Epithelium Atrophy Overlying Drusen with Fundus Autofluorescence vs. Spectral Domain Optical Coherence Tomography

Journal of Ophthalmology, 2020
Purpose. This study aims to find out which tool, fundus autofluorescence (FAF) or spectral domain optical coherence tomography (SD-OCT), is more sensitive in detecting retinal pigment epithelium (RPE) demise overlying drusen and can, therefore, help ...
Anabel Rodríguez, Marc Biarnés, Rosa M. Coco-Martin, Anna Sala-Puigdollers, Jordi Monés   +4 more
doaj   +1 more source

Dual Knockout Models of the Spatially and Functionally Conserved rgra and rgrb Zebrafish Genes Reveal the Requirement of RGR for the Integrity of Cone‐Mediated Photopic Vision, the Photopic Visual Cycle and Bruch's Membrane Morphology

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
This study investigates the role of the vision gene RGR using novel dual knockout zebrafish models. The loss of rgra and rgrb results in zebrafish larvae having reduced visual function and altered retinoid profiles under light but not dark conditions. The OKR phenotype is enhanced under higher light intensities.
Grace Ruddin, Tess McCann, Joanna J. Kaylor, Michelle M. Fox, John D. Fehilly, Rebecca Ward, Adam Faulkner, Ailís L. Moran, Kieran Wynne, Roxana A. Radu, Michael G. Monaghan, Stephen D. Thorpe, Gabriel H. Travis, Breandán N. Kennedy   +13 more
wiley   +1 more source

POSSIBILITIES OF MODERN IMAGING TECHNIQUES IN DIAGNOSTICS OF OPTIC NERVE DRUSEN (LITERATURE REVIEW)

Acta Biomedica Scientifica, 2016
With the introduction and development of new diagnostic techniques, the relevance of drusen of the optic nerve diagnostics is increasing. Existing imaging techniques alone or in their various combinations cannot allow to confirm optic nerve drusen in all
E. E. Ioyleva, E. A. Kabanova, E. S. Kotova   +2 more
doaj   +1 more source

Retinal disease classification from OCT images using EfficientNetB3 with neutrosophic similarity score enhancement

Journal of Applied Clinical Medical Physics, Volume 27, Issue 5, May 2026.
Abstract Purpose Automated classification of retinal diseases from optical coherence tomography (OCT) images plays a significant role in supporting early diagnosis and clinical decision‐making. In this study, a deep learning (DL) framework is developed by integrating a neutrosophic similarity score (NSS) with the EfficientNetB3 to improve image ...
Devi M, G. Hannah Grace
wiley   +1 more source

Association of drusen deposition with choroidal intercapillary pillars in the aging human eye

, 2004
PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H, Bird, AC, Tufail, A, Jeffery, G, Luthert, P, Lengyel, I   +5 more
core  

Association of soft drusen with risk of all-cause and specific-cause mortality in the National Health and Nutrition Examination Survey, 2005 to 2008

Scientific Reports
The aim of this study is to investigate the correlation between soft drusen and the likelihood of mortality from all causes and specific ailments within a representative United States population.
Huihui Wu, Xiaofang Wang, Yajun Liu, Ye Zhang, Ruiwen Cheng, Mengru Su, Xinghong Sun, Feng Jiang   +7 more
doaj   +1 more source

Anterior ischemic optic neuropathy in association with optic nervehead drusen

Indian Journal of Ophthalmology, 2014
Optic nerve head drusen (ONHD) are incidental ophthalmologic finding in the optic nerve. Patients with ONHD are often asymptomatic, but sometimes present with transient visual obscuration′s (TVO), the reported incidence of which is 8.6%. Optic nerve head
Bharathi Megur, Deepak Megur, Umesh Megur, Sandeep Reddy   +3 more
doaj   +1 more source

Safety, Tolerability, and Pharmacokinetics of Mirvetuximab Soravtansine in Chinese Patients With Folate Receptor α‐Positive Advanced Ovarian Cancer

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Folate receptor α (FRα) is a glycosylphosphatidylinositol‐anchored protein that facilitates folate transport and has emerged as a promising therapeutic target for ovarian cancer, particularly due to its association with tumor progression.
Yongsheng Li, Li Yuan, Ge Lou, Hongbing Cai, Yuzhi Li, Fenghu Li, Li Wang, Xingtao Long, Yi Gong, Chaonan Zhu, Li Li, June Xu, Qi Zhou   +12 more
wiley   +1 more source