Results 81 to 90 of about 31,224 (320)

TSPO ligands promote cholesterol efflux and suppress oxidative stress and inflammation in choroidal endothelial cells [PDF]

, 2018
Choroidal endothelial cells supply oxygen and nutrients to retinal pigment epithelial (RPE) cells and photoreceptors, recycle metabolites, and dispose of metabolic waste through the choroidal blood circulation.
Bartholomew, Christopher, Biswas, Lincoln, Farhan, Fahad, Reilly, James, Shu, Xinhua   +4 more
core   +1 more source

Fundus Autofluorescence Lifetimes and Spectral Features of Soft Drusen and Hyperpigmentation in Age-Related Macular Degeneration

Translational Vision Science & Technology, 2020
Purpose To investigate the autofluorescence lifetimes as well as spectral characteristics of soft drusen and retinal hyperpigmentation in age-related macular degeneration (AMD).
M. Hammer, Rowena Schultz, Somar M. Hasan, L. Sauer, M. Klemm, Lukas Kreilkamp, L. Zweifel, R. Augsten, D. Meller   +8 more
semanticscholar   +1 more source

Sophisticated Ensemble Deep Learning Approaches for Multilabel Retinal Disease Classification in Medical Imaging

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT This paper introduces a novel ensemble Deep learning (DL)‐based Multi‐Label Retinal Disease Classification (MLRDC) system, known for its high accuracy and efficiency. Utilising a stacking ensemble approach, and integrating DenseNet201, EfficientNetB4, EfficientNetB3 and EfficientNetV2S models, exceptional performance in retinal disease ...
Asghar Amir, Tariqullah Jan, Mohammad Haseeb Zafar, Shadan Khan Khattak   +3 more
wiley   +1 more source

Abundance and multimodal visibility of soft drusen in early age-related macular degeneration: a clinicopathologic correlation.

Retina, 2020
PURPOSE To determine the abundance and multimodal visibility of drusen and basal linear deposit (BLinD) in early age-related macular degeneration (AMD).
Ling Chen, J. Messinger, K. Sloan, Jessica Wong, A. Roorda, J. Duncan, C. Curcio   +6 more
semanticscholar   +1 more source

Evaluating the Therapeutic Potential of Superoxide Dismutase in a Rat Model of Wet Age‐Related Macular Degeneration

FASEB BioAdvances, EarlyView.
Oral Superoxide Dismutase Therapy Mitigates Choroidal Neovascularization in a Laser‐Induced Rat Model of Wet Age‐Related Macular Degeneration. Oral Administration of GF103, a Superoxide Dismutase From Bacillus amyloliquefaciens, Reduces Choroidal Neovascularization (CNV) in a Laser‐Induced CNV Rat Model.
Hyun Chul Jeong, Chang Sik Cho, Jeong Hyun Kim, Inik Chang, Jeong Hun Kim   +4 more
wiley   +1 more source

Photo-damage, photo-protection and age-related macular degeneration [PDF]

, 2015
Age-related macular degeneration (AMD) is a degenerative retinal disease that causes blindness in people 60-65 years and older, with the highest prevalence appearing in people 90 years-old or more.
Marquioni Ramella, Melisa Daniela, Suburo, Angela Maria   +1 more
core   +1 more source

The Optic Disc Drusen Studies Consortium Recommendations for Diagnosis of Optic Disc Drusen Using Optical Coherence Tomography

Journal of neuro-ophthalmology, 2017
Background: Making an accurate diagnosis of optic disc drusen (ODD) is important as part of the work-up for possible life-threatening optic disc edema.
L. Malmqvist, L. Bursztyn, F. Costello, K. Digre, J. A. Fraser, C. Fraser, B. Katz, Mitchell Lawlor, A. Petzold, P. Sibony, J. Warner, M. Wegener, S. Wong, S. Wong, S. Hamann   +14 more
semanticscholar   +1 more source

Differential Organ Ageing Is Associated With Age‐Related Macular Degeneration

Aging Cell, EarlyView.
Using the UK Biobank, this study trained neural networks to estimate the biological age of individuals according to markers of organ function. Computing the difference between the estimated organ age and chronological age yielded an estimate for accelerated or slowed ageing.
Anastasios Papadam, Arimantas Lionikas, Felix Grassmann   +2 more
wiley   +1 more source

Drusen classification and quantification in pseudophakic postmortem eyes implanted with or without blue-light filtering intraocular lenses

The Pan-American Journal of Ophthalmology
Purpose: To investigate the effect of blue-light filtering intraocular lenses on drusen formation in postmortem eyes via histopathological analysis.
Emmanuel Issa Bassam Nassrallah, Christina Mastromonaco, Emily Marcotte, Emma Youhnovska, Mohamed Abdouh, Miguel N. Burnier   +5 more
doaj   +1 more source

Multimodal Imaging and En Face OCT Detection of Calcified Drusen in Eyes with Age-Related Macular Degeneration

Ophthalmology Science, 2022
Purpose: En face OCT imaging was investigated as a method for the detection and monitoring of calcified drusen in eyes with nonexudative age-related macular degeneration (AMD). Design: Retrospective case series of a prospective study.
Jeremy Liu, BS, Rita Laiginhas, MD, Mengxi Shen, MD, Yingying Shi, MD, Jianqing Li, MD, Omer Trivizki, MD, Nadia K. Waheed, MD, Giovanni Gregori, PhD, Philip J. Rosenfeld, MD, PhD   +8 more
doaj