Results 81 to 90 of about 32,629 (301)

Fundus Autofluorescence Lifetimes and Spectral Features of Soft Drusen and Hyperpigmentation in Age-Related Macular Degeneration

Translational Vision Science & Technology, 2020
Purpose To investigate the autofluorescence lifetimes as well as spectral characteristics of soft drusen and retinal hyperpigmentation in age-related macular degeneration (AMD).
M. Hammer, Rowena Schultz, Somar M. Hasan, L. Sauer, M. Klemm, Lukas Kreilkamp, L. Zweifel, R. Augsten, D. Meller   +8 more
semanticscholar   +1 more source

A variance components factor model for genetic association studies: a Bayesian analysis.

, 2010
Studies of gene-trait associations for complex diseases often involve multiple traits that may vary by genotype groups or patterns. Such traits are usually manifestations of lower-dimensional latent factors or disease syndromes.
Nonyane, BAS, Whittaker, JC
core   +1 more source

Laser treatment of drusen to prevent progression to advanced age-related macular degeneration. [PDF]

, 2009
BACKGROUND: Drusen are amorphous yellowish deposits beneath the sensory retina. People with drusen, particularly large drusen, are at higher risk of developing age-related macular degeneration (AMD).
Abdelsalam, Alexander, Anonymous, Anonymous, Bressler, Bressler, Bressler, Brown, Chakravarthy, Chong, Cleasby, Duvall, Elbourne, Evans, Figueroa, Figueroa, Figueroa, Figueroa, Fine, Frennesson, Frennesson, Frennesson, Frennesson, Frennesson, Friberg, Gass, Glanville, Gross-Jendroska, Grunwald, Guidry, Guymer, Hassell, Ho, Ho, Holz, Kaiser, Kertes, Klein, Little, Little, Maguire, Maguire, Mangione, Olk, Owen, Owens, Owens, Owens, Pauleikhoff, Pauleikhoff, Phipps, Prenner, Regillo, Rodanant, Rosenbaltt, Sarks, Sarraf, Sbarbaro, Sigelman, Sivagnanavel, Smith, Stoltz, Vingerling, Wetzig, White, Ying, Young   +66 more
core   +1 more source

Abundance and multimodal visibility of soft drusen in early age-related macular degeneration: a clinicopathologic correlation.

Retina, 2020
PURPOSE To determine the abundance and multimodal visibility of drusen and basal linear deposit (BLinD) in early age-related macular degeneration (AMD).
Ling Chen, J. Messinger, K. Sloan, Jessica Wong, A. Roorda, J. Duncan, C. Curcio   +6 more
semanticscholar   +1 more source

Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]

, 2017
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio, Reilly, James, Shu, Xinhua, Tiano, Luca, Tohari, Ali Mohammad, Zhang, Xun, Zhou, Xinzhi   +6 more
core   +1 more source

Integrated Roles of Systemic Diseases and Serum Biomarkers in the Incidence of Age‐Related Macular Degeneration: The UK Biobank Study

Medicine Bulletin, EarlyView.
ABSTRACT Background To evaluate the associations of systemic diseases with AMD incidence and explore whether polygenic risk score (PRS) for AMD influences these associations. To assess the impacts of polymorbidities and serum biomarkers on AMD risk. Methods This prospective study of 471156 AMD‐free UK Biobank participants assessed systemic diseases ...
Jun Yu, Yuzhou Zhang, Mary Ho, Ka Wai Kam, Shi Song Rong, Alvin L. Young, Chi Pui Pang, Clement C. Tham, Jason C. Yam, Li Jia Chen   +9 more
wiley   +1 more source

Prevalence of age-related macular degeneration in Nakuru, Kenya: a cross-sectional population-based study. [PDF]

, 2013
BACKGROUND: Diseases of the posterior segment of the eye, including age-related macular degeneration (AMD), have recently been recognised as the leading or second leading cause of blindness in several African countries.
Bastawrous, Andrew, Foster, Allen, Kuper, Hannah, Leung, Irene, Mathenge, Wanjiku, Peto, Tunde   +5 more
core   +6 more sources

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao, Linxin Wei, Huan Chen, Yan Luo, Youxin Chen, Zhikun Yang   +5 more
wiley   +1 more source

Outcome and safety of multiple photodynamic therapy sessions in chronic central serous chorioretinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose This study evaluates the effectiveness and safety of multiple PDT sessions for cases of persistent and recurrent subretinal fluid (SRF) in chronic central serous chorioretinopathy (CSC). Methods This multicentre, retrospective cohort study included patients aged ≥18 years with chronic CSC who received at least two sessions of PDT at ...
Jennifer M. Chang‐Wolf, Elon H. C. van Dijk, Kamal el Boujdaini, Mitchel van Straaten, Thomas J. van Rijssen, Reinier O. Schlingemann, Camiel J. F. Boon, Roselie M. H. Diederen   +7 more
wiley   +1 more source

Interactive Image Analysis in Age-related Macular Degeneration (AMD) and Stargardt Disease (STGD) [PDF]

, 2008
The literature of the last three decades is replete with automatic methods for retinal image analysis. Acceptance has been limited due to post-processing or tuning requirements that may be just as time consuming as the original manual methods.
Busuioc, Mihai, Chen, Jian, Laine, Andrew F., Lee, Noah, Smith, R. Theodore   +4 more
core   +2 more sources