Results 81 to 90 of about 25,200 (252)

Documentation of Intraretinal Retinal Pigment Epithelium Migration via High-Speed Ultrahigh-Resolution Optical Coherence Tomography [PDF]

open access: yes, 2010
Purpose To describe the features of intraretinal retinal pigment epithelium (RPE) migration documented on a prototype spectral-domain, high-speed, ultrahigh-resolution optical coherence tomography (OCT) device in a group of patients with early to ...
Chen, Yueli   +6 more
core   +1 more source

The Proteomics of Drusen [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2014
The formation of extracellular deposits known as drusen below the macular region of the retina correlates with increased risk of severe visual loss from age-related macular degeneration (AMD). Inflammation and complement dysregulation contribute to AMD progression; however, disease mechanisms remain incompletely defined.
openaire   +2 more sources

Self‐Supervised Learning‐Based Framework for Speckle Reduction of Optical Coherence Tomography Images Using Frame Interpolation

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 12, December 2025.
In summary, a self‐supervised end‐to‐end framework for OCT image despeckling is proposed, without access to unpaired noisy–clean images or paired noisy–noisy images for training. The despeckling performance has been evaluated on 150 subjects from five retina datasets (121 subjects) and one middle ear dataset (29 subjects). Optical coherence tomography (
Zhiyi Jiang   +3 more
wiley   +1 more source

Novel grid combined with peripheral distortion correction for ultra-widefield image grading of age-related macular degeneration

open access: yesClinical Ophthalmology, 2017
Patrick Oellers,1,* Inês Laíns,1,2,* Steven Mach,1 Shady Garas,1 Ivana K Kim,1 Demetrios G Vavvas,1 Joan W Miller,1 Deeba Husain,1 John B Miller1 1Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical ...
Oellers P   +8 more
doaj  

RETINAL ANGIOMATOUS PROLIFERATION: A Quantitative Analysis of the Fundoscopic Features of the Fellow Eye [PDF]

open access: yes, 2015
PURPOSE: To quantitatively analyze and compare the fundoscopic features between fellow eyes of retinal angiomatous proliferation and typical exudative age-related macular degeneration and to identify possible predictors of neovascularization. METHODS:
Costa, MA   +6 more
core   +1 more source

Mainstream Artificial Intelligence Technologies in Contemporary Ophthalmology

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 12, December 2025.
This review explores the latest artificial intelligence (AI) technologies in ophthalmology, focusing on four key data types: medical imaging, electronic health records, robotic‐assisted surgery, and genomics. It examines the structural features, use cases, clinical goals, and evaluation metrics of various AI algorithms, while also introducing emerging ...
Shiqi Yin   +9 more
wiley   +1 more source

Association of soft drusen with risk of all-cause and specific-cause mortality in the National Health and Nutrition Examination Survey, 2005 to 2008

open access: yesScientific Reports
The aim of this study is to investigate the correlation between soft drusen and the likelihood of mortality from all causes and specific ailments within a representative United States population.
Huihui Wu   +7 more
doaj   +1 more source

Fundus Autofluorescence Lifetimes and Spectral Features of Soft Drusen and Hyperpigmentation in Age-Related Macular Degeneration [PDF]

open access: gold, 2020
Martin Hammer   +8 more
openalex   +1 more source

Quantitatively Measured Anatomic Location and Volume of Optic Disc Drusen: An Enhanced Depth Imaging Optical Coherence Tomography Study [PDF]

open access: yes, 2017
Optic disc drusen (ODD) are found in up to 2.4% of the population and are known to cause visual field defects. The purpose of the current study was to investigate how quantitatively estimated volume and anatomic location of ODD influence optic nerve ...
Dahl, Vedrana Andersen   +4 more
core   +2 more sources

Investigating the effects of complement loci CFH and ARMS2/HTRA1 on Alzheimer Disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Late‐onset Alzheimer Disease (LOAD) shares multiple pathologic features and genetic risk factors with Age‐related Macular Degeneration (AMD). Amyloid‐beta (Ab) forms amyloid plaques in the brain and aggregates with other proteins and lipids to form drusen deposits in the retina of AMD eyes.
Noel C. Moore   +25 more
wiley   +1 more source

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