Results 61 to 70 of about 17,907 (178)

Development and adoption of Kernza—A perennial grain crop for sustainable agriculture

PLANTS, PEOPLE, PLANET, EarlyView.
Annual cereal grains account for ~50% of human food calories, but cultivation of these crops has resulted in major environmental and social issues worldwide. For nearly three decades, researchers have been breeding intermediate wheatgrass—a perennial cool‐season grass—to serve as the world's first commercial‐scale perennial grain crop to improve ...
Jessica L. Gutknecht, James A. Anderson, George Annor, Prabin Bajgain, Timothy E. Crews, Colin Cureton, Lee DeHaan, Erin Meier, Tessa Peters, Valentín Picasso, Evelyn C. Reilly, Aaron Reser, Tara Ritter, Aubrey Streit Krug, Nicole Tautges, Jacob M. Jungers   +15 more
wiley   +1 more source

Age‐related macular degeneration severity and risk of Alzheimer's disease in older adults in a prospective, community‐based cohort study

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Age‐related macular degeneration (AMD) is associated with higher risk of Alzheimer's disease (AD), but how AD risk changes as AMD progresses remains unclear.
Chloe A. Krakauer, Luke Reilly, Yu‐Ru Su, Rod L. Walker, Dana Lee, Vilaipone A. Xaiyamuangchanh, David J. Cronkite, Nicole M. Gatto, Paul K. Crane, Emily Y. Chew, David E. Arterburn, Cecilia S. Lee   +11 more
doaj   +1 more source

Dobesilate for dry age-related macular degeneration

Journal of Biomedical Science and Engineering, 2013
We have evaluated the effects of intravitreal dobesilate, a synthetic fibroblast growth factor inhibitor, in patients with dry age-related macular degeneration, an inflammatory-related retinal disease without available treatment up to date. 36 eyes from 36 patients with dry age-related macular degeneration were treated with a single intravitreal ...
Pedro Cuevas, Luis A. Outeiriño, Carlos Azanza, Javier Angulo, Guillermo Giménez-Gallego   +4 more
openaire   +2 more sources

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice

Disease Models & Mechanisms, 2018
Non-exudative age-related macular degeneration, a prevalent cause of blindness, is a progressive and degenerative disease characterized by alterations in Bruch's membrane, retinal pigment epithelium, and photoreceptors exclusively localized in the macula.
Hernán H. Dieguez, Horacio E. Romeo, María F. González Fleitas, Marcos L. Aranda, Georgia A. Milne, Ruth E. Rosenstein, Damián Dorfman   +6 more
doaj   +1 more source

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

Clinical effectiveness of nutrof total supplement for Dry age-related macular Degeneration

Российский офтальмологический журнал, 2018
The paper’s purpose is to assess visual functions in patients with dry age-related macular degeneration (AMD) who receive antioxidant Nutrof Total supplement. Three groups of patients over 50 were examined.
E. N. Eskina, A. V. Belogurova, M. A. Stepanova   +2 more
doaj   +1 more source

Treatment of the dry form of age-related macular degeneration: the studied present and promising future [PDF]

Клиническая офтальмология, 2022
N.G. Glazko1,2, O.A. Kanaeva2, M.H. Rabadanova2 1Hospital for War Veterans No. 2, Moscow, Russian Federation 2Pirogov Russian National Research Medical University, Moscow, Russian Federation Age-related macular degeneration (AMD) is the main
N.G. Glazko, O.A. Kanaeva, M.H. Rabadanova   +2 more
doaj