Results 1 to 10 of about 706,442 (245)

Comparison of Clarus, Optos, and Heidelberg Systems for Geographic Atrophy Area Measurements [PDF]

Ophthalmology Science
Purpose: To compare geographic atrophy (GA) area measurements across 3 modern fundus autofluorescence (FAF) imaging platforms: Heidelberg Spectralis, Optos California, and Zeiss Clarus 700.
Jacob Bogost, DO, Thomas Saunders, OD, Jennifer Heathcote, PhD, Jeong W. Pak, PhD, David Lopez, MS, Colin Froines, MD, Barbara Blodi, MD, Roomasa Channa, MD, Kathleen Schildroth, MD, Kevin Kurt, OD, Mihai Mititelu, MD, MPH, Kimberly Stepien, MD, Jonathan S. Chang, MD, Michael Altaweel, MD, Justin Gottlieb, MD, Karina Conlin, OD, Patricia Sabb, MD, Nayan Patel, OD, Amitha Domalpally, MD, PhD   +18 more
doaj   +2 more sources

Comparing Accuracies of Length-Type Geographic Atrophy Growth Rate Metrics Using Atrophy-Front Growth Modeling

Ophthalmology Science, 2022
Purpose: To compare the accuracies of the previously proposed square-root-transformed and perimeter-adjusted metrics for estimating length-type geographic atrophy (GA) growth rates. Design: Cross-sectional and simulation-based study. Participants: Thirty-
Yingying Shi, James G Fujimoto, Philip Rosenfeld   +2 more
exaly   +3 more sources

Clinical Characteristics and Progression of Pachychoroid and Conventional Geographic Atrophy

Ophthalmology Science
Purpose: To elucidate the clinical characteristics and progression rates of pachychoroid and conventional geographic atrophy (GA). Design: Retrospective, multicenter, observational study.
Ayako Takahashi, Yasuo Yanagi, Hideki Koizumi   +2 more
exaly   +3 more sources

Gradeability and Reproducibility of Geographic Atrophy Measurement in GATHER-1, a Phase II/III Randomized Interventional Trial

Ophthalmology Science
Objective: To validate GATHER-1 inclusion criteria and the study’s primary anatomic end point by assessing the reproducibility of geographic atrophy (GA) measurements and factors that affect reproducibility.
Sandra Stinnett, Angela Li, Dilraj Grewal   +2 more
exaly   +3 more sources

Linking the microbiome to the complement system in geographic atrophy [PDF]

npj Genomic Medicine
Age-related macular degeneration (AMD) is the leading cause of vision loss in the aged population with the late stage geographic atrophy (GA). Risk factors for AMD include age, genetic variants in the complement system, nutritional factors, and ...
Livia Spörri, Justyna M. Studer, Marco Kreuzer, Jérémy Rotzetter, Daniel Schärer, Carlo R. Largiadèr, Damian Jaggi, Martin S. Zinkernagel, Denise C. Zysset-Burri   +8 more
doaj   +2 more sources

Automated OCT-tailored and same-visit biomarker-targeted microperimetry in geographic atrophy [PDF]

Scientific Reports
This proof-of-concept study developed and validated an automated, biomarker-targeted, real-time microperimetry (MP) approach for individualized structure-function assessment in geographic atrophy (GA).
Merle Tratnig-Frankl, Lukas Kuchernig, Klaudia Birner, Simon Schürer-Waldheim, Anna Eidenberger, Johannes Schrittwieser, Markus Gumpinger, Georg Faustmann, Magdalena Baratsits, Oliver Leingang, Gregor S. Reiter, Ursula Schmidt-Erfurth   +11 more
doaj   +2 more sources

SWAU-Net: Longitudinal Prediction of Geographic Atrophy via Sliding-Window Attention [PDF]

Life
Age-related macular degeneration (AMD) is the leading cause of central vision loss in aging populations. Geographic atrophy (GA) is the advanced, non-neovascular form of AMD.
Peter Racioppo, Ziyuan Chris Wang, SriniVas R. Sadda, Zhihong Jewel Hu   +3 more
doaj   +2 more sources

Targeted High-Density Microperimetry Testing of Nascent Geographic Atrophy in Age-Related Macular Degeneration

Ophthalmology Science
Purpose: To examine the effectiveness of a targeted high-density microperimetry testing strategy for detecting visual sensitivity abnormalities in eyes with nascent geographic atrophy (nGA) when compared with standard central microperimetry testing ...
Zhichao Wu, Robyn Guymer, Lauren Hodgson   +2 more
exaly   +3 more sources

Biofeedback Fixation Training in the Rehabilitation of Patients with Geographic Atrophy [PDF]

Life
Geographic atrophy (GA) is a progressive cause of central vision loss with limited rehabilitation options. This prospective case series aimed to evaluate the effects of biofeedback fixation training (BFT) on visual function and vision-related quality of ...
Kristóf Vörös, Illés Kovács, Gréta Kézdy, Ágnes Élő, Zsuzsa Szilágyi, Mirella Barboni, Zsuzsa Récsán, Zoltán Zsolt Nagy, Monika Ecsedy   +8 more
doaj   +2 more sources

Estimating Uncertainty of Geographic Atrophy Segmentations with Bayesian Deep Learning

Ophthalmology Science
Purpose: To apply methods for quantifying uncertainty of deep learning segmentation of geographic atrophy (GA). Design: Retrospective analysis of OCT images and model comparison.
Anand E Rajesh
exaly   +3 more sources