Results 21 to 30 of about 42,548 (287)

Comparing Accuracies of Length-Type Geographic Atrophy Growth Rate Metrics Using Atrophy-Front Growth Modeling

Ophthalmology Science, 2022
Purpose: To compare the accuracies of the previously proposed square-root-transformed and perimeter-adjusted metrics for estimating length-type geographic atrophy (GA) growth rates. Design: Cross-sectional and simulation-based study. Participants: Thirty-
Eric M. Moult, PhD, Yingying Shi, MD, Liang Wang, BS, Siyu Chen, PhD, Nadia K. Waheed, MD, MPH, Giovanni Gregori, PhD, Philip J. Rosenfeld, MD, PhD, James G. Fujimoto, PhD   +7 more
doaj   +1 more source

In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. [PDF]

, 2017
Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD).
Cunefare, David, Farsiu, Sina, Garzel, Laura, Munevar, Christian, Roberts, Jeffrey, Thomasy, Sara, Tieu, Eric, Wong, Brittany, Yiu, Glenn   +8 more
core   +2 more sources

Serum lipids in adults with late age-related macular degeneration: a case-control study

Lipids in Health and Disease, 2019
Background Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized.
Richard D. Semba, Ruin Moaddel, Mary Frances Cotch, Fridbert Jonasson, Gudny Eiriksdottir, Tamara B. Harris, Lenore J. Launer, Kai Sun, Ronald Klein, Debra A. Schaumberg, Pálmi Jónsson, Vilmundur Gudnason, Luigi Ferrucci   +12 more
doaj   +1 more source

Complement C3 variant and the risk of age-related macular degeneration [PDF]

, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM, Bird, AC, Clayton, DG, Deary, IJ, Dhillon, B, Genetic Factors AMD Study G, Hayward, C, Khan, JC, Matharu, BK, Moore, AT, Morgan, J, Redmond, E, Sepp, T, Shahid, H, Thurlby, DA, Wright, AF, Yates, JRW   +16 more
core   +1 more source

Test–retest variability of microperimetry in geographic atrophy

International Journal of Retina and Vitreous, 2020
Purpose Microperimetry (MP) allows for measurement of retinal sensitivity at precise locations and is now commonly employed as a clinical trial endpoint.
A. Yasin Alibhai, Nihaal Mehta, Sheila Hickson-Curran, Carlos Moreira-Neto, Emily S. Levine, Elias Reichel, Jay S. Duker, Nadia K. Waheed   +7 more
doaj   +1 more source

Prevalence of age-related macular degeneration in Nakuru, Kenya: a cross-sectional population-based study. [PDF]

, 2013
BACKGROUND: Diseases of the posterior segment of the eye, including age-related macular degeneration (AMD), have recently been recognised as the leading or second leading cause of blindness in several African countries.
Bastawrous, Andrew, Foster, Allen, Kuper, Hannah, Leung, Irene, Mathenge, Wanjiku, Peto, Tunde   +5 more
core   +6 more sources

Treating patients with geographic atrophy: are we there yet?

International Journal of Retina and Vitreous, 2023
Geographic atrophy (GA) is a progressive degenerative disease that significantly contributes to visual impairment in individuals aged 50 years and older. The development of GA is influenced by various modifiable and non-modifiable risk factors, including
Bani Antonio-Aguirre, J. Fernando Arevalo   +1 more
doaj   +1 more source

Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]

, 2017
Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria, Fawzi, Amani, Gill, Manjot, Ma, Jeffrey, Nesper, Peter, Skondra, Dimitra   +5 more
core   +3 more sources

Choriocapillaris Degeneration in Geographic Atrophy [PDF]

The American Journal of Pathology, 2019
Early age-related macular degeneration (AMD) is characterized by degeneration of the choriocapillaris, the vascular supply of retinal photoreceptor cells. We assessed vascular loss during disease progression in the choriocapillaris and larger vessels in the deeper choroid.
Elliott H. Sohn, Miles J. Flamme-Wiese, S. Scott Whitmore, Grefachew Workalemahu, Alexander G. Marneros, Erin A. Boese, Young H. Kwon, Kai Wang, Michael D. Abramoff, Budd A. Tucker, Edwin M. Stone, Robert F. Mullins   +11 more
openaire   +2 more sources

GEOGRAPHIC ATROPHY [PDF]

Retina, 2016
There is a lack of agreement regarding the types of lesions and clinical conditions that should be included in the term "geographic atrophy." Varied and conflicting views prevail throughout the literature and are currently used by retinal experts and other health care professionals.We reviewed the nominal definition of the term "geographic atrophy" and
S. Schmitz-Valckenberg, S. Sadda, G. Staurenghi, E. Y. Chew, M. Fleckenstein, F. G. Holz   +5 more
openaire   +3 more sources