Results 21 to 30 of about 21,775 (287)

Geographic Atrophy [PDF]

JAMA Ophthalmology, 2014
Geographic atrophy (GA) is the major cause of blind registration in Western communities, although, with few exceptions, it is less common than choroidal neovascular disease. The variation of phenotype implies that age-related macular degeneration (AMD) does not follow the same course from one case to another and that phenotyping may be important before
Alan C, Bird, Rachel L, Phillips, Gregory S, Hageman   +2 more
openaire   +3 more sources

Geographic Atrophy in Age-Related Macular Degeneration

Ophthalmology Science, 2023
Purpose: To examine disease progression in age-related macular degeneration (AMD) at 2 distinct stages, progression to geographic atrophy (GA) versus GA expansion, by comparison of the risk and protective factors at each stage.
Tiarnan D.L. Keenan, BM BCh, PhD
doaj   +1 more source

Geographic atrophy: pathophysiology and current therapeutic strategies

Frontiers in Ophthalmology, 2023
Geographic atrophy (GA) is an advanced stage of age-related macular degeneration (AMD) that leads to gradual and permanent vision loss. GA is characterized by the loss of photoreceptor cells and retinal pigment epithelium (RPE), leading to distinct ...
Kalpana Rajanala, Farokh Dotiwala, Arun Upadhyay   +2 more
doaj   +1 more source

Choroidal Round Hyporeflectivities in Geographic Atrophy. [PDF]

PLoS ONE, 2016
In geographic atrophy (GA), choroidal vessels typically appear on structural optical coherence tomography (OCT) as hyperreflective round areas with highly reflective borders.
Eleonora Corbelli, Riccardo Sacconi, Luigi Antonio De Vitis, Adriano Carnevali, Alessandro Rabiolo, Lea Querques, Francesco Bandello, Giuseppe Querques   +7 more
doaj   +1 more source

Longitudinal foveal fluorescence lifetime characteristics in geographic atrophy using fluorescence lifetime imaging ophthalmoscopy (FLIO). [PDF]

, 2021
PURPOSE Short foveal fluorescence lifetimes (fFLT) in geographic atrophy are typically found in eyes with foveal sparing (FS) but may also occur in eyes without FS.
Martin S. Zinkernagel, Damian Jaggi, Dysli, Chantal, Sebastian Wolf, Lincke, Joel-Benjamin, Yasmin Solberg, Solberg, Yasmin, Joel-Benjamin Lincke, Zinkernagel, Martin, Chantal Dysli, Jaggi, Damian, Wolf, Sebastian   +11 more
core   +1 more source

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD. [PDF]

, 2009
Age-related macular degeneration (AMD) is a prevalent cause of blindness in Western societies. Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly been
Weber, Bernhard H. F., Fleckenstein, Monika, Frank G Holz, Weber, B. H., Hendrik P N Scholl, Scholl, Hendrik P. N., Tim Becker, Ulrich Mansmann, Weinberger Andreas W. A., Schmitz-Valckenberg Steffen, Mackensen, F., Herold Christine, Holz, Frank G, Scholl Hendrik P. N., Weber, Bernhard H F, Andreas Mössner, Keilhauer, Claudia N, Scholl, Hendrik P N, Fritsche, Lars G., Steffen Schmitz-Valckenberg, Schmitz-Valckenberg, S., Claudia N Keilhauer, Weinberger, A. W., Fritsche, Lars G, Weinberger, Andreas W. A., Pauleikhoff, D., Becker, T., Andreas W A Weinberger, Adrion, Christine, Mansmann Ulrich, Weber Bernhard H. F., Becker Tim, Göbel, Arno, Mackensen Friederike, Holz, F. G., Monika Fleckenstein, Göbel, A., Adrion Christine, Holz Frank G., Scholl, H. P., Friederike Mackensen, Mackensen, Friederike, Mansmann, Ulrich, Göbel Arno, Becker, Tim, Fleckenstein Monika, Mössner, Andreas, Lars G Fritsche, Fritsche Lars G., Keilhauer Claudia N., Schmitz-Valckenberg, Steffen, Fritsche, L. G., Herold, Christine, Arno Göbel, Daniel Pauleikhoff, Weinberger, Andreas, Christine Herold, Mansmann, U., Christine Adrion, Bernhard H F Weber, Mössner, A., Pauleikhoff, Daniel, Keilhauer, C. N., Herold, C., Holz, Frank G., Adrion, C., Mößner Andreas, Pauleikhoff Daniel, Fleckenstein, M.   +68 more
core   +1 more source

Is There a Relationship Between Use of Anti-Vascular Endothelial Growth Factor Agents and Atrophic Changes in Age-Related Macular Degeneration Patients?

Türk Oftalmoloji Dergisi, 2018
Choroidal neovascularization due to age-related macular degeneration (AMD) is currently treated successfully with anti-vascular endothelial growth factor (VEGF) intravitreal agents.
Süleyman Kaynak, Mahmut Kaya, Derya Kaya   +2 more
doaj   +1 more source

Serum lipids in adults with late age-related macular degeneration: a case-control study

Lipids in Health and Disease, 2019
Background Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized.
Richard D. Semba, Ruin Moaddel, Mary Frances Cotch, Fridbert Jonasson, Gudny Eiriksdottir, Tamara B. Harris, Lenore J. Launer, Kai Sun, Ronald Klein, Debra A. Schaumberg, Pálmi Jónsson, Vilmundur Gudnason, Luigi Ferrucci   +12 more
doaj   +1 more source

Comparing Accuracies of Length-Type Geographic Atrophy Growth Rate Metrics Using Atrophy-Front Growth Modeling

Ophthalmology Science, 2022
Purpose: To compare the accuracies of the previously proposed square-root-transformed and perimeter-adjusted metrics for estimating length-type geographic atrophy (GA) growth rates. Design: Cross-sectional and simulation-based study. Participants: Thirty-
Eric M. Moult, PhD, Yingying Shi, MD, Liang Wang, BS, Siyu Chen, PhD, Nadia K. Waheed, MD, MPH, Giovanni Gregori, PhD, Philip J. Rosenfeld, MD, PhD, James G. Fujimoto, PhD   +7 more
doaj   +1 more source

Test–retest variability of microperimetry in geographic atrophy

International Journal of Retina and Vitreous, 2020
Purpose Microperimetry (MP) allows for measurement of retinal sensitivity at precise locations and is now commonly employed as a clinical trial endpoint.
A. Yasin Alibhai, Nihaal Mehta, Sheila Hickson-Curran, Carlos Moreira-Neto, Emily S. Levine, Elias Reichel, Jay S. Duker, Nadia K. Waheed   +7 more
doaj   +1 more source